Lewis-Sumner syndrome
Synonyms: MADSAM · Multifocal acquired demyelinating sensory and motor neuropathy
- Type
- Clinical subtype
- Group
- Subtype of disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare acquired demyelinating polyneuropathy characterized by asymmetrical distal weakness of the upper or lower extremities and motor dysfunction with adult onset. It is considered to be a variant of chronic inflammatory demyelinating polyneuropathy.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Lewis-Sumner syndrome | MADSAM · Multifocal acquired demyelinating sensory and motor neuropathy |
| fr | Syndrome de Lewis-Sumner | Neuropathie démyélinisante multifocale sensitivomotrice acquise |
| de | Lewis-Sumner-Syndrom | MADSAM · Multifokale erworbene demyelinisierende sensorische und motorische Neuropathie |
| es | Síndrome de Lewis-Summer | |
| it | Sindrome di Lewis-Sumner | MADSAM |
| nl | Syndroom van Lewis-Sumner | MADSAM · Multifocale verworven demyeliniserende sensorische en motorische neuropathie |
| pt | Síndrome Lewis-Sumner | |
| pl | Zespół Lewisa i Sumnera | MADSAM · Wieloogniskowa nabyta demielinizująca neuropatia czuciowa i ruchowa |
| cs | Lewisův-Sumnerův syndrom | MADSAM · Multifokální získaná demyelinizační senzorická a motorická neuropatie · Lewis-Sumnerův syndrom |
| uk | Синдром Льюїса-Самнера | MADSAM · Мультифокальна набута демієлінізуюча сенсорна та моторна нейропатія |
| zh | Lewis-Sumner综合征 | 多灶性获得性脱髓鞘感觉和运动神经病 |
| tr | Lewis-Sumner sendromu | MADSAM · Multifokal edinsel demiyelinizan duyusal ve motor nöropati |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G61.8 | NTBT | attributed | validated |
| ICD-11 | 8C01.3 | NTBT | index | validated |
| MONDO | 0018826 | E | validated | |
| UMLS | C1695985 | E | validated | |
| GARD | 13070 | E | validated | |
| MedDRA | 10065580 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:2932Chronic inflammatory demyelinating polyneuropathy
rare neurological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-9 / 1 000 000 | 0.9 / 100 000 | Europe | Value and class | Not yet validated | 19260065[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/48162
- This record as JSON: /data/d/48162.json