Avian influenza
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare, infectious disease characterized by variable severity and outcome, ranging from mild upper respiratory tract infection with fever and cough, to influenza-like illness with rapid progression to severe pneumonia, sepsis with shock, acute respiratory distress syndrome and even death. Additional manifestations may include conjunctivitis, nausea, abdominal pain, diarrhea, vomiting, multiple organ dysfunction, and encephalopathy.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Avian influenza | |
| fr | Grippe aviaire | |
| de | Vogelgrippe | Aviäre Influenza |
| es | Gripe aviar | Gripe aviaria |
| it | Influenza aviaria | Influenza da H5N1 |
| nl | Vogelgriep | Aviaire influenza |
| pt | Gripe aviária | |
| pl | Ptasia grypa | Grypa H5N1 |
| cs | Ptačí chřipka | |
| uk | Пташиний грип | |
| zh | 禽流感 | |
| tr | Kuş gribi |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | J09 | NTBT | attributed | validated |
| ICD-11 | 1E31 | NTBT | index | validated |
| MONDO | 0018695 | E | validated | |
| MeSH | D005585 | E | validated | |
| UMLS | C0016627 | E | validated | |
| MedDRA | 10064097 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:101944Rare pulmonary disease
rare respiratory diseases - ORPHA:163585Rare viral disease
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
3 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Cases/families | 826 cases | Worldwide | Case(s) | Validated | World Health Organization 2015[OTHER] | |
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | ORPHANET |
| Point prevalence | <1 / 1 000 000 | — | Europe | Class only | Validated | ORPHANET_World Health Organization 2015[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
41 annotations · validated 2020-03-31| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0012735 | Cough | |
| HP:0012378 | Fatigue | |
| HP:0001945 | Fever | |
| HP:0003326 | Myalgia | |
| HP:0025439 | Pharyngitis | |
| Frequent (79-30%) | ||
| HP:0011227 | Elevated circulating C-reactive protein concentration | |
| HP:0025179 | Ground-glass opacification on pulmonary HRCT | |
| HP:0002315 | Headache | |
| HP:0012418 | Hypoxemia | |
| HP:0001882 | Leukopenia | |
| HP:0001888 | Lymphopenia | |
| HP:0031246 | Nonproductive cough | |
| HP:0002113 | Pulmonary infiltrates | |
| HP:0001873 | Thrombocytopenia | |
| Occasional (29-5%) | ||
| HP:0002027 | Abdominal pain | |
| HP:0100749 | Chest pain | |
| HP:0000509 | Conjunctivitis | |
| HP:0002014 | Diarrhea | |
| HP:0002094 | Dyspnea | |
| HP:0025435 | Increased circulating lactate dehydrogenase concentration | |
| HP:0002202 | Pleural effusion | |
| HP:0002090 | Pneumonia | |
| HP:0031245 | Productive cough | |
| HP:0002878 | Respiratory failure | |
| HP:0005268 | Spontaneous abortion | |
| HP:0002013 | Vomiting | |
| Very rare (<4-1%) | ||
| HP:0001919 | Acute kidney injury | |
| HP:0001635 | Congestive heart failure | |
| HP:0005521 | Disseminated intravascular coagulation | |
| HP:0003236 | Elevated circulating creatine kinase concentration | |
| HP:0002910 | Elevated circulating hepatic transaminase concentration | |
| HP:0012115 | Hepatitis | |
| HP:0003073 | Hypoalbuminemia | |
| HP:0002383 | Infectious encephalitis | |
| HP:0001287 | Meningitis | |
| HP:0012486 | Myelitis | |
| HP:0002107 | Pneumothorax | |
| HP:0002098 | Respiratory distress | |
| HP:0003201 | Rhabdomyolysis | |
| HP:0100806 | Sepsis | |
| HP:0002789 | Tachypnea | |
Run the differential on the 5 obligate / very frequent terms
Annotation source: 28159162[PMID]_31668198[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/454836
- This record as JSON: /data/d/454836.json