raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:438279

Human infection by orthopoxvirus

Type
Disease
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

A rare viral disease characterized by fever, malaise, lymphadenopathy, and a maculopapular exanthema spreading from the site of infection to other regions of the body. The skin lesions eventually dry out and may leave behind scars. The most relevant orthopox species for human disease after the eradication of the variola virus, which was responsible for smallpox, are the monkeypox virus and the cowpox virus. Infections with these viruses typically take a benign course.

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Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enHuman infection by orthopoxvirus
frInfection humaine à l'orthopoxvirus
deHumane Orthopockenviren-Infektion
esInfección humana por orthopoxvirus
itInfezione umana da orthopoxvirus
nlHumane infectie door orthopoxvirus
ptInfecção humana por ortopoxvírus
plZakażenie ludzkim ortopokswirusem
csHumánní infekce orthopoxviry
ukІнфікування людини ортопоксвірусом
zh正痘病毒感染
trOrtopoksvirus kaynaklı insan enfeksiyonu

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10B03BTNTattributedvalidated
ICD-10B04BTNTattributedvalidated
ICD-10B08.0BTNTattributedvalidated
ICD-111E70BTNTspecificvalidated
ICD-111E71BTNTspecificvalidated
ICD-111E72BTNTspecificvalidated
ICD-111E73BTNTspecificvalidated
ICD-111E74BTNTspecificvalidated
MONDO0018583Evalidated
UMLSC1532229Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

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Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

Codes that Orphanet moved or referred to this one:

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Genes

0 direct

Orphanet records no gene directly on this code.

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Prevalence and incidence

1 record
TypeClassValueAreaQualificationValidationSource
Point prevalence<1 / 1 000 000—EuropeClass onlyValidatedEuropean Medicines Agency 2010[OTHER]

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

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HPO phenotypes

Orphanet has no HPO annotation for this code in this release.

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Sources for this card