raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:43117

Acute tricyclic antidepressant poisoning

Type
Particular clinical situation in a disease or syndrome
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

A rare, potentially lethal intoxication characterized by life-threatening arrhythmias (sinus tachycardias, premature ventricular contractions, ventricular arrhythmias), anticholinergic toxidrome (mydriasis, dry mucous membrane, tachycardia, hypertension), central nervous system toxicity (lethargy, coma, myoclonic jerks), refractory hypotension and sudden death.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enAcute tricyclic antidepressant poisoning
frIntoxication aiguë par les antidépresseurs tricycliques
deTrizyklische Antidepressiva, akute Vergiftung
esIntoxicación aguda por antidepresivos tricíclicos
itIntossicazione acuta da antidepressivi triciclici
nlAcute tricyclisch antidepressivumvergiftiging
ptIntoxicação aguda por antidepressivos tricíclicos
plOstre zatrucie trójcyklicznymi lekami przeciwdepresyjnymi
csAkutní otrava tricyklickými antidepresivy
ukГостре отруєння трициклічними антидепресантами
zh急性三环类抗忧郁药中毒
trAkut trisiklik antidepresan zehirlenmesi

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10T43.0NTBTattributedvalidated
ICD-11NE60NTBTattributedvalidated
MONDO0018547Evalidated
UMLSC5681319Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

1 record
TypeClassValueAreaQualificationValidationSource
Point prevalenceUnknown—WorldwideClass onlyNot yet validatedORPHANET

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

Orphanet has no HPO annotation for this code in this release.

7

Sources for this card