Eosinophilic colitis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adult, Infancy
- Status
- active
A rare gastroenterologic disease characterized by extensive eosinophilic infiltration of the colon in the absence of any known cause of secondary intestinal eosinophilia. Patients present with abdominal pain, nausea, vomiting, diarrhea, gastrointestinal bleeding, malabsorption, and/or weight loss. Symptoms do not correlate with the extent of the disease, which can be segmental or pancolonic. Blood testing may show peripheral eosinophilia. The condition has a bimodal age distribution, with a first peak in neonates and a second peak in young adulthood.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Eosinophilic colitis | |
| fr | Colite à éosinophiles | Colite éosinophilique |
| de | Eosinophile Kolitis | |
| es | Colitis eosinofílica | |
| it | Colite eosinofila | |
| nl | Eosinofiele colitis | |
| pt | Colite eosinofílica | |
| pl | Eozynofilowe zapalenie jelit | |
| cs | Eosinofilní kolitida | |
| uk | Еозинофільний коліт | |
| zh | 嗜酸细胞性结肠炎 | |
| tr | Eozinofilik kolit |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | K52.8 | NTBT | attributed | validated |
| ICD-11 | DB33.2Y | NTBT | index | validated |
| MONDO | 0018439 | E | validated | |
| UMLS | C0267448 | E | validated | |
| MedDRA | 10057271 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:402029Primary eosinophilic gastrointestinal disease
rare gastroenterological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Cases/families | 196 cases | Worldwide | Case(s) | Validated | 22012125[PMID] | |
| Point prevalence | <1 / 1 000 000 | — | Worldwide | Class only | Validated | ORPHANET_22012125[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/402035
- This record as JSON: /data/d/402035.json