ORPHA:391490
Adult-onset myasthenia gravis
Synonyms: Adult-onset acquired myasthenia · Adult-onset autoimmune myasthenia gravis
- Type
- Clinical subtype
- Group
- Subtype of disorder
- Inheritance
- Multigenic/multifactorial, Not applicable
- Age of onset
- Adult
- Status
- active
A rare autoimmune disorder of the neuromuscular junction characterized by fatigable muscle weakness with frequent ocular signs and/or generalized muscle weakness, and occasionally associated with thymoma.
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Adult-onset myasthenia gravis | Adult-onset acquired myasthenia · Adult-onset autoimmune myasthenia gravis |
| fr | Myasthénie auto-immune de l'adulte | Myasthenia gravis de l'adulte · Myasthénie acquise de l'adulte |
| de | Myasthenia gravis mit Beginn im Erwachsenenalter | Autoimmune Myasthenia gravis mit Beginn im Erwachsenenalter · Erworbene Myasthenie mit Beginn im Erwachsenenalter |
| es | Miastenia grave de inicio en el adulto | Miastenia adquirida de inicio en el adulto · Miastenia grave autoinmune de inicio en el adulto |
| it | Miastenia gravis a esordio nell'età adulta | Miastenia acquisita a esordio nell'età adulta · Miastenia grave autoimmune a esordio nell'età adulta · Miastenia gravis autoimmune a esordio nell'età adulta |
| nl | Myasthenia gravis met aanvang op volwassen leeftijd | Auto-immune myasthenia gravis met volwassen aanvang · Verworven myasthenie met volwassen aanvang |
| pt | Miastenia gravis com início no adulto | |
| pl | Miastenia o początku w wieku dorosłym | Miastenia autoimmunologiczna o początku w wieku dorosłym · Miastenia nabyta o początku w wieku dorosłym |
| cs | Adultní forma myasthenia gravis | Adultní získaná myastenie · Autoimunitní myasthenia gravis s nástupem v dospělosti |
| uk | Miastenia gravis з дебютом у дорослому віці | Набута у дорослому віці міастенія · Автоімунна міастенія, що починається у дорослих |
| zh | 成人起病重症肌无力 | 成人起病自身免疫性重症肌无力 |
| tr | Erişkin başlangıçlı myastenia gravis | Erişkin-başlangıçlı edinsel miyasteni · Erişkin-başlangıçlı otoimmün miyastenia gravis |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G70.0 | NTBT | attributed | validated |
| ICD-11 | 8C60 | NTBT | attributed | validated |
| MONDO | 0018324 | E | validated | |
| UMLS | C5680024 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:589Myasthenia gravis
rare neurological diseases; rare ophthalmic disorders
No children.
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
5 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 31.8 / 100 000 | Serbia | Value and class | Validated | 23363926[PMID] |
| Annual incidence | 1-9 / 100 000 | 1.33 / 100 000 | Serbia | Value and class | Validated | 23363926[PMID] |
| Point prevalence | 1-5 / 10 000 | 17 / 100 000 | United States | Value and class | Validated | [EXPERT]_ORPHANET |
| Point prevalence | 1-5 / 10 000 | 28 / 100 000 | United Kingdom | Value and class | Validated | [EXPERT]_ORPHANET |
| Point prevalence | 1-5 / 10 000 | — | Europe | Class only | Validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/391490
- This record as JSON: /data/d/391490.json