Interstitial cystitis
Synonyms: Bladder pain syndrome · IC/BPS · IC/PBS · Interstitial cystitis/bladder pain syndrome · Interstitial cystitis/painful bladder syndrome · Painful bladder syndrome
- Type
- Disease
- Group
- Disorder
- Inheritance
- Unknown
- Age of onset
- All ages
- Status
- active
A rare non-infectious, chronic and most often progressive disease of the urinary bladder. It is characterized by varying combinations and extent of pain, urinary frequency (pollakisuria), nocturia and urgency. Interstitial cystitis (IC) has a broad intersection with Bladder Pain Syndrome (BPS) and Overactive Bladder (OAB).
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Interstitial cystitis | Bladder pain syndrome · IC/BPS · IC/PBS · Interstitial cystitis/bladder pain syndrome · Interstitial cystitis/painful bladder syndrome · Painful bladder syndrome |
| fr | Syndrome douloureux vésical | Cystite interstitielle · IC/BPS · IC/PBS · Syndrome de la douleur vésicale · Syndrome de la vessie douloureuse |
| de | Interstitielle Cystitis | Blasenschmerz-Syndrom · IC/BPS · Interstitielle Cystitis/Blasenschmerzsyndrom · Interstitielle Zystitis |
| es | Cistitis intersticial | SDV/CI · SVD/CI · Síndrome de dolor vesical · Síndrome de dolor vesical/cistitis intersticial · Síndrome de vejiga dolorosa · Síndrome de vejiga dolorosa/cistitis intersticial |
| it | Cistite interstiziale | Sindrome della vescica dolorosa |
| nl | Interstitiële cystitis | Blaaspijnsyndroom · IC/BPS · IC/PBS · Interstitiële cystitis/blaaspijnsyndroom · Interstitiële cystitis/pijnlijke blaassyndroom · Pijnlijke blaassyndroom |
| pt | Cistite intersticial | |
| pl | Śródmiąższowe zapalenie pęcherza moczowego | IC/BPS · IC/PBS · Zespół bólu pęcherza · Zespół bolesnego pęcherza |
| cs | Intersticiální cystitida | Syndrom bolesti močového měchýře · Syndrom bolestivého měchýře |
| uk | Інтерстиціальний цистит | Больовий синдром у сечовому міхурі · IC/BPS · IC/PBS · Інтерстиціальний цистит/больовий синдром сечового міхура · Інтерстиціальний цистит/синдром хворобливого сечового міхура · Синдром хворобливого сечового міхура |
| zh | 间质性膀胱炎 | 间质性膀胱炎/膀胱疼痛综合征 |
| tr | İnterstisyel sistit | IC/BPS · IC/PBS · Mesane ağrısı sendromu · Ağrılı mesane sendromu · İnterstisyel sistit/mesane ağrısı sendromu · İnterstisyel sistit/ağrılı mesane sendromu |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | N30.1 | E | specific | validated |
| ICD-11 | GC00.3 | E | specific | validated |
| MONDO | 0018301 | E | validated | |
| MeSH | D018856 | E | validated | |
| UMLS | C0282488 | E | validated | |
| MedDRA | 10011796 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:101433Rare urogenital disease
rare urogenital diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
4 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | — | Europe | Class only | Not yet validated | ORPHANET_1137336[PMID] |
| Point prevalence | 1-5 / 10 000 | 10.6 / 100 000 | Finland | Value and class | Validated | 1137336[PMID] |
| Point prevalence | 1-5 / 10 000 | 30 / 100 000 | United States | Value and class | Validated | ISBN:978-4471-3295-0[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.66 / 100 000 | Finland | Value and class | Validated | 1137336[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
19 annotations · validated 2023-09-22| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0000014 | Abnormality of the bladder | |
| HP:0000078 | Abnormality of the genital system | |
| HP:0000058 | Abnormality of the labia | |
| HP:0000140 | Abnormality of the menstrual cycle | |
| HP:0000795 | Abnormality of the urethra | |
| HP:0030016 | Dyspareunia | |
| HP:0100518 | Dysuria | |
| HP:0000009 | Functional abnormality of the bladder | |
| HP:0000017 | Nocturia | |
| HP:0034267 | Pelvic pain | |
| HP:0100515 | Pollakisuria | |
| HP:0100577 | Urinary bladder inflammation | |
| HP:0000012 | Urinary urgency | |
| Frequent (79-30%) | ||
| HP:0011118 | Abnormality of tumor necrosis factor secretion | |
| HP:0002960 | Autoimmunity | |
| HP:0000716 | Depression | |
| HP:0011227 | Elevated circulating C-reactive protein concentration | |
| Occasional (29-5%) | ||
| HP:0000142 | Abnormality of the vagina | |
| HP:0500005 | Anal pain | |
Run the differential on the 12 obligate / very frequent terms
Annotation source: 34033350[PMID]_22057291[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/37202
- This record as JSON: /data/d/37202.json