Acute opioid intoxication
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare intoxication with opioids, a large group of alkaloid analgesics, mainly characterized by miosis (pinpoint pupil), respiratory depression (bradypnea/apnea) and central nervous system depression (sedation or coma). Other manifestations include hypotension, reduced bowel motility, hypothermia and hypoglycemia. Naloxone, a competitive inhibitor of the mu-opioid receptor, is a potent antagonist and is used as the antidote for opioid intoxication.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Acute opioid intoxication | |
| fr | Intoxication aiguë par les opioïdes | |
| de | Opiat-Vergiftung, akute | |
| es | Intoxicación aguda por opioides | |
| it | Intossicazione acuta da oppioidi | |
| nl | Acute intoxicatie door opioïd | |
| pt | Intoxicação aguda por opióides | |
| pl | Ostre zatrucie opioidami | |
| cs | Akutní intoxikace opiáty | |
| uk | Гостра опіоїдна інтоксикація | |
| zh | 急性阿片中毒 | |
| tr | Akut opioid zehirlenmesi |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | T40.0 | BTNT | specific | validated |
| ICD-10 | T40.1 | BTNT | specific | validated |
| ICD-10 | T40.2 | BTNT | specific | validated |
| ICD-11 | 6C43.3 | E | specific | validated |
| MONDO | 0018173 | E | validated | |
| MONDO | 18173 | E | validated | |
| UMLS | C5848046 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:556508Rare disorder due to poisoning
rare disorders due to toxic effects
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/35889
- This record as JSON: /data/d/35889.json