Mercury poisoning
Synonyms: Hydrargyria · Mercurialism · Mercury intoxication
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
Mercury poisoning is caused mainly through ingestion or inhalation of any of the 3 forms of mercury, elemental, organic, and inorganic. Exposure to elemental mercury affects the pulmonary (inhalation of mercury vapors causes coughing, chills, fever, shortness of breath), dermatological (mild swelling, vesiculation, scaling, irritation, urticaria, erythema and allergic contact dermatitis accompanied by pain), and peripheral and central nervous (CNS) systems (depression, paranoia, extreme irritability, hallucinations, inability to concentrate, memory loss, hands, head, lips, tongue, jaw and eyelids tremors, weight loss, perpetually low body temperature, drowsiness, headaches, insomnia, fatigue). Exposure to inorganic mercury generally causes development of a metallic taste, local oropharyngeal pain, nausea, vomiting, bloody diarrhea, colic abdominal pain, renal dysfunction and, neurologic abnormalities; while that to organic mercury can lead to delayed neurotoxicity.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Mercury poisoning | Hydrargyria · Mercurialism · Mercury intoxication |
| fr | Intoxication au mercure | Hydrargyrie · Mercurialisme |
| de | Quecksilbervergiftung | Merkurialismus · Quecksilber-Intoxikation |
| es | Intoxicación por mercurio | Envenenamiento por mercurio · Hidrargiria · Mercurialismo |
| it | Avvelenamento da mercurio | Mercurialismo · Idrargiria · Intossicazione da mercurio |
| nl | Kwikvergiftiging | Hydrargyria · Kwikintoxicatie · Mercurialisme |
| pt | Envenenamento por mercúrio | Hidrargiria · Intoxicação por mercúrio · Mercurialismo |
| pl | Zatrucie rtęcią | Intoksykacja rtęcią · Merkurializm · Rtęcica |
| cs | Otrava rtutí | = en |
| uk | Отруєння ртуттю | Гідраргірія · Меркуріалізм · Ртутна інтоксикація |
| zh | 汞中毒 | = en |
| tr | Cıva zehirlenmesi | Civa zehirlenmesi · Merkürlülük · Cıva zehirlenmesi |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | T56.1 | E | specific | validated |
| ICD-11 | NE61 | NTBT | index | validated |
| MONDO | 0018020 | E | validated | |
| MeSH | D008630 | E | validated | |
| UMLS | C0025427 | E | validated | |
| GARD | 7021 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:556508Rare disorder due to poisoning
rare disorders due to toxic effects
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | — | Europe | Class only | Validated | European Medicines Agency 2012[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
21 annotations · validated 2016-12-22| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Frequent (79-30%) | ||
| HP:0002500 | Abnormal cerebral white matter morphology | |
| HP:0001919 | Acute kidney injury | |
| HP:0002039 | Anorexia | |
| HP:0001289 | Confusion | |
| HP:0002094 | Dyspnea | |
| HP:0001332 | Dystonia | |
| HP:0002574 | Episodic abdominal pain | |
| HP:0002572 | Episodic vomiting | |
| HP:0003324 | Generalized muscle weakness | |
| HP:0000822 | Hypertension | |
| HP:0002900 | Hypokalemia | |
| HP:0002615 | Hypotension | |
| HP:0100785 | Insomnia | |
| HP:0006515 | Interstitial pneumonitis | |
| HP:0007185 | Loss of consciousness | |
| HP:0002018 | Nausea | |
| HP:0002098 | Respiratory distress | |
| HP:0002878 | Respiratory failure | |
| HP:0001250 | Seizure | |
| HP:0001649 | Tachycardia | |
| HP:0001337 | Tremor | |
Annotation source: 26807265[PMID]_26678598[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/330021
- This record as JSON: /data/d/330021.json