raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:31205

Rat-bite fever

Type
Disease
Group
Disorder
Age of onset
All ages
Status
active

A rare bacterial zoonosis characterized by fever, arthralgia and a rash predominantly affecting the extremities, typically occurring after a bite or scratch from infected rats. The disease may be caused by <i>Streptobacillus moniliformis</i>, also known as streptobacillosis, or by <i>Spirillum minus</i>, also known as sodoku.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enRat-bite fever
frFièvre due aux morsures de rat
deRattenbiss-Fieber
esFiebre causada por mordeduras de rata
itFebbre da morso di ratto
nlRattenbeetkoortsRattenbeetziekte
ptFebre por mordedura de rato
plGorączka od ugryzienia szczura
csHorečka z krysího kousnutí
ukЛихоманка від укусу щура
zh鼠咬热
trSıçan humması ateşi

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10A25.0BTNTspecificvalidated
ICD-10A25.1BTNTspecificvalidated
ICD-10A25.9BTNTspecificvalidated
ICD-111B90Especificvalidated
MONDO0006941Evalidated
MeSHD011906Evalidated
UMLSC0034686Evalidated
GARD9557Evalidated
MedDRA10037904Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

Children (2):

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

1 record
TypeClassValueAreaQualificationValidationSource
Point prevalenceUnknown—WorldwideClass onlyNot yet validatedORPHANET

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

32 annotations · validated 2019-11-19
HPOTerm (as annotated by Orphanet)Diagnostic
Very frequent (99-80%)
HP:0001945Fever
Frequent (79-30%)
HP:0002829Arthralgia
HP:0001369Arthritis
HP:0012282Morbilliform rash
HP:0000988Skin rash
HP:0002013Vomiting
Occasional (29-5%)
HP:0003418Back pain
HP:0025143Chills
HP:0002014Diarrhea
HP:0002374Diminished movement
HP:0012219Erythema nodosum
HP:0002315Headache
HP:0002840Lymphadenitis
HP:0040186Maculopapular exanthema
HP:0003326Myalgia
HP:0040313Oligoarthritis
HP:0025439Pharyngitis
HP:0200039Pustule
HP:0025145Rigors
HP:0040189Scaling skin
HP:0100806Sepsis
HP:0003095Septic arthritis
HP:0001824Weight loss
Very rare (<4-1%)
HP:0025181Abdominal aseptic abscess
HP:0001903Anemia
HP:0100584Endocarditis
HP:0001287Meningitis
HP:0012819Myocarditis
HP:0001733Pancreatitis
HP:0011850Parotitis
HP:0001701Pericarditis
HP:0025230Tendonitis

Run the differential on the 1 obligate / very frequent terms

Annotation source: 31015812[PMID]_19008054[PMID]_23529964[PMID]

7

Sources for this card