Nocardiosis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare bacterial infection characterized by various clinical manifestations depending on the site of infection, caused by the Gram-positive bacillus <i>Nocardia</i>. The most common presentation is lung infection, which typically follows pathogen inhalation. Dissemination to other organs may occur, especially among immunocompromised patients. Primary skin and soft-tissue infection follows skin inoculation.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Nocardiosis | |
| fr | Nocardiose | |
| de | Nokardiose | |
| es | Nocardiosis | |
| it | Nocardiosi | |
| nl | Nocardiose | |
| pt | Nocardiose | |
| pl | Nokardioza | |
| cs | Nokardióza | |
| uk | Нокардіоз | |
| zh | 诺卡菌病 | |
| tr | Nokardiyoz |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A43.0 | BTNT | specific | validated |
| ICD-10 | A43.1 | BTNT | specific | validated |
| ICD-10 | A43.8 | BTNT | specific | validated |
| ICD-10 | A43.9 | BTNT | specific | validated |
| ICD-11 | 1C1B | E | specific | validated |
| ICD-11 | 1C1B.0 | BTNT | specific | validated |
| ICD-11 | 1C1B.1 | BTNT | specific | validated |
| ICD-11 | 1C1B.Y | BTNT | attributed | validated |
| MONDO | 0017776 | E | validated | |
| MeSH | D009617 | E | validated | |
| UMLS | C0028242 | E | validated | |
| GARD | 7210 | E | validated | |
| MedDRA | 10029444 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163582Rare bacterial infectious disease
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
| Annual incidence | 1-9 / 1 000 000 | 0.6 / 100 000 | Canada | Value and class | Validated | 20636427[PMID]_ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
52 annotations · validated 2019-11-19| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0001945 | Fever | |
| Frequent (79-30%) | ||
| HP:0032016 | Abnormal sputum | |
| HP:0031864 | Bacteremia | |
| HP:0100749 | Chest pain | |
| HP:0002094 | Dyspnea | |
| HP:0012378 | Fatigue | |
| HP:0002721 | Immunodeficiency | |
| HP:0002090 | Pneumonia | |
| HP:0031245 | Productive cough | |
| Occasional (29-5%) | ||
| HP:0002039 | Anorexia | |
| HP:0030049 | Brain abscess | |
| HP:0025143 | Chills | |
| HP:0000509 | Conjunctivitis | |
| HP:0031292 | Cutaneous abscess | |
| HP:0000620 | Dacryocystitis | |
| HP:0002097 | Emphysema | |
| HP:0002315 | Headache | |
| HP:0002105 | Hemoptysis | |
| HP:0100523 | Liver abscess | |
| HP:0002840 | Lymphadenitis | |
| HP:0030166 | Night sweats | |
| HP:0031246 | Nonproductive cough | |
| HP:0200026 | Ocular pain | |
| HP:0002754 | Osteomyelitis | |
| HP:0001701 | Pericarditis | |
| HP:0002202 | Pleural effusion | |
| HP:0002102 | Pleuritis | |
| HP:0002107 | Pneumothorax | |
| HP:0004372 | Reduced consciousness | |
| HP:0002098 | Respiratory distress | |
| HP:0002878 | Respiratory failure | |
| HP:0100806 | Sepsis | |
| HP:0032169 | Severe infection | |
| HP:0001482 | Subcutaneous nodule | |
| HP:0011450 | Unusual CNS infection | |
| HP:0002013 | Vomiting | |
| HP:0001824 | Weight loss | |
| Very rare (<4-1%) | ||
| HP:0001654 | Abnormal heart valve morphology | |
| HP:0045026 | Abnormal mediastinum morphology | |
| HP:0000834 | Abnormality of the adrenal glands | |
| HP:0100658 | Cellulitis | |
| HP:0012424 | Chorioretinitis | |
| HP:0100584 | Endocarditis | |
| HP:0004302 | Functional motor deficit | |
| HP:0002383 | Infectious encephalitis | |
| HP:0000491 | Keratitis | |
| HP:0001287 | Meningitis | |
| HP:0002586 | Peritonitis | |
| HP:0100532 | Scleritis | |
| HP:0000575 | Scotoma | |
| HP:0001250 | Seizure | |
| HP:0100646 | Thyroiditis | |
Run the differential on the 1 obligate / very frequent terms
Annotation source: 31363440[PMID]_22469352[PMID]_28626172[PMID]_29146497[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/31204
- This record as JSON: /data/d/31204.json