Delayed encephalopathy due to carbon monoxide poisoning
Synonyms: Delayed encephalopathy due to CO poisoning
- Type
- Disease
- Group
- Disorder
- Age of onset
- All ages
- Status
- active
A rare neurologic disease characterized by delayed onset of encephalopathy typically within a few weeks after acute carbon monoxide poisoning. The most common symptoms are cognitive impairment, personality changes, and movement disorder including parkinsonism, among others. Prognosis is good with a high rate of spontaneous recovery within a year.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Delayed encephalopathy due to carbon monoxide poisoning | Delayed encephalopathy due to CO poisoning |
| fr | Syndrome post-intervallaire par intoxication au monoxyde de carbone | |
| de | Verzögerte Kohlenmonoxidenzephalopathie | Verzögerte Enzephalopathie durch CO-Intoxikation |
| es | Encefalopatía retardada por intoxicación por monóxido de carbono | Encefalopatía retardada por intoxicación por CO |
| it | Encefalopatia tardiva da avvelenamento da monossido di carbonio | Parkinsonismo indotto da CO |
| nl | Vertraagde encefalopathie door intoxicatie door koolmonoxide | Vertraagde encefalopathie door CO-intoxicatie |
| pt | Encefalopatia tardia induzida pelo monóxido de carbono | Parkinson induzido pelo monóxido de carbono |
| pl | Parkinsonizm indukowany tlenkiem węgla | Parkinsonizm indukowany CO |
| cs | Parkinsonismus indukovaný oxidem uhelnatým | Parkinsonismus indukovaný CO |
| uk | Відстрочена енцефалопатія внаслідок отруєння чадним газом | Відстрочена енцефалопатія внаслідок отруєння СО |
| zh | 一氧化碳中毒致迟发性脑病 | 一氧化碳中毒所致迟发性脑病 |
| tr | Karbon monoksit zehirlenmesine bağlı gecikmiş ensefalopati | CO zehirlenmesine bağlı gecikmiş ensefalopati |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G21.2 | NTBT | attributed | validated |
| ICD-11 | 8D43.0Y | NTBT | index | validated |
| UMLS | C0393565 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:556508Rare disorder due to poisoning
rare disorders due to toxic effects - ORPHA:306679Rare parkinsonian syndrome due to intoxication
rare neurological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
0 recordsNo prevalence record in this release.
HPO phenotypes
9 annotations · validated 2018-03-30| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0002518 | Abnormal periventricular white matter morphology | |
| HP:0000708 | Atypical behavior | |
| HP:0012706 | Elevated brain choline level by MRS | |
| HP:0002354 | Memory impairment | |
| HP:0012708 | Reduced brain N-acetyl aspartate level by MRS | |
| Frequent (79-30%) | ||
| HP:0002817 | Abnormality of the upper limb | |
| HP:0002067 | Bradykinesia | |
| HP:0004673 | Decreased facial expression | |
| HP:0002063 | Rigidity | |
Run the differential on the 5 obligate / very frequent terms
Annotation source: 10927805[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/306686
- This record as JSON: /data/d/306686.json