raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:295

Fetal parvovirus syndrome

Synonyms: Mother-to-child transmission of parvovirus syndrome · Parvovirus antenatal infection

Type
Malformation syndrome
Group
Disorder
Inheritance
Not applicable
Age of onset
Antenatal, Neonatal
Status
active

Foetal parvovirus syndrome is a foetopathy likely to occur when a pregnant woman is infected by parvovirus B19. In adults, the virus causes a butterfly erythema infectiosum (also called Fifth Disease; 'slapped cheek disease') and flu-like symptoms with symmetric polyarthralgias, which usually do not warrant prenatal diagnosis.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enFetal parvovirus syndromeMother-to-child transmission of parvovirus syndrome · Parvovirus antenatal infection
frEmbryopathie à parvovirusInfection anténatale au parvovirus
deParvovirus-EmbryopathieParvovirus-Infektion durch Mutter-Kind-Übertragung · Parvovirus-Infektion, vorgeburtliche
esSíndrome de parvovirus fetalInfección prenatal por parvovirus · Transmisión materna del síndrome de parvovirus
itEmbriopatia da parvovirusInfezione prenatale da parvovirus
nlFoetaal parvovirussyndroomAntenatale parvovirusinfectie · Transmissie van moeder op kind van parvovirussyndroom
ptSíndrome de parvovírus fetalInfeção pré-natal por parvovírus
plParwowirusowy zespół płoduParwowirusowa infekcja płodowa
csFetální parvovirový syndromPrenatální parvovirová infekce
ukФетальний парвовірусний синдромПередача парвовірусного синдрому від матері до дитини · Парвовірусна антенатальна інфекція
zh胎儿巨细小病毒综合征母婴传播型细小病毒综合征
trFetal parvovirus sendromuParvovirus antenatal enfeksiyon · Parvovirüs sendromunun anneden çocuğa geçişi

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10P35.8NTBTattributedvalidated
ICD-11KA62.7Especificvalidated
MONDO0017453Evalidated
MeSHC536301Evalidated
UMLSC2931167Evalidated
GARD4236Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (2):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

1 record
TypeClassValueAreaQualificationValidationSource
Point prevalenceUnknown—WorldwideClass onlyNot yet validatedORPHANET

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

9 annotations · validated 2016-06-01
HPOTerm (as annotated by Orphanet)Diagnostic
Very frequent (99-80%)
HP:0001903Anemia
HP:0001541Ascites
HP:0001789Hydrops fetalis
HP:0001873Thrombocytopenia
Occasional (29-5%)
HP:0000478Abnormality of the eye
HP:0000504Abnormality of vision
HP:0001639Hypertrophic cardiomyopathy
HP:0010880Increased nuchal translucency
HP:0001511Intrauterine growth retardation

Run the differential on the 4 obligate / very frequent terms

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Sources for this card