{"orpha":295,"name":"Fetal parvovirus syndrome","type":"Malformation syndrome","group":"Disorder","status":"active","flags":[],"synonyms":["Mother-to-child transmission of parvovirus syndrome","Parvovirus antenatal infection"],"definition":"Foetal parvovirus syndrome is a foetopathy likely to occur when a pregnant woman is infected by parvovirus B19. In adults, the virus causes a butterfly erythema infectiosum (also called Fifth Disease; 'slapped cheek disease') and flu-like symptoms with symmetric polyarthralgias, which usually do not warrant prenatal diagnosis.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-295/","orphanet_url":"https://www.orpha.net/en/disease/detail/295","names":{"fr":{"name":"Embryopathie à parvovirus","synonyms":["Infection anténatale au parvovirus"],"definition":"Le syndrome d'embryopathie à parvovirus est une foetopathie qui peut survenir lorsqu'au cours de la grossesse, la mère est infectée par le parvovirus B19. Chez les adultes, le virus se manifeste par un érythème en ailes de papillon (aussi appelée cinquième maladie) et des symptômes identiques à ceux de la grippe avec une polyarthralgie symétrique qui, en général, ne conduit pas au diagnostic prénatal."},"de":{"name":"Parvovirus-Embryopathie","synonyms":["Parvovirus-Infektion durch Mutter-Kind-Übertragung","Parvovirus-Infektion, vorgeburtliche"]},"es":{"name":"Síndrome de parvovirus fetal","synonyms":["Infección prenatal por parvovirus","Transmisión materna del síndrome de parvovirus"],"definition":"El síndrome por parvovirus es una fetopatía que se puede producir cuando una mujer embarazada se infecta con parvovirus B19. En adultos causa un eritema infeccioso en mariposa (también llamado Quinta enfermedad; 'enfermedad de la bofetada en la mejilla'), y síntomas parecidos a la gripe con poliartralgia simétrica, que generalmente no permiten un diagnóstico prenatal."},"it":{"name":"Embriopatia da parvovirus","synonyms":["Infezione prenatale da parvovirus"]},"nl":{"name":"Foetaal parvovirussyndroom","synonyms":["Antenatale parvovirusinfectie","Transmissie van moeder op kind van parvovirussyndroom"],"definition":"Een foetopathie die kan voorkomen wanneer een zwangere vrouw wordt geïnfecteerd door parvovirus B19. Bij volwassenen veroorzaakt het virus vlindervormig erythema infectiosum (ook gekend als de vijfde ziekte, appelwangen) en griepachtige symptomen met symmetrische polyartralgie, die doorgaans geen prenatale diagnose toelaten."},"pt":{"name":"Síndrome de parvovírus fetal","synonyms":["Infeção pré-natal por parvovírus"]},"pl":{"name":"Parwowirusowy zespół płodu","synonyms":["Parwowirusowa infekcja płodowa"]},"cs":{"name":"Fetální parvovirový syndrom","synonyms":["Prenatální parvovirová infekce"]},"uk":{"name":"Фетальний парвовірусний синдром","synonyms":["Передача парвовірусного синдрому від матері до дитини","Парвовірусна антенатальна інфекція"],"definition":"Foetal parvovirus syndrome is a foetopathy likely to occur when a pregnant woman is infected by parvovirus B19. In adults, the virus causes a butterfly erythema infectiosum (also called Fifth Disease; 'slapped cheek disease') and flu-like symptoms with symmetric polyarthralgias, which usually do not warrant prenatal diagnosis."},"zh":{"name":"胎儿巨细小病毒综合征","synonyms":["母婴传播型细小病毒综合征"]},"tr":{"name":"Fetal parvovirus sendromu","synonyms":["Parvovirus antenatal enfeksiyon","Parvovirüs sendromunun anneden çocuğa geçişi"]}},"xrefs":[{"source":"ICD-10","code":"P35.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"KA62.7","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"648536096"},{"source":"MONDO","code":"0017453","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"C536301","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C2931167","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"4236","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":232035,"name":"Infectious embryofetopathy","classifications":[147,203,216]},{"orpha":138059,"name":"Teratogenic Pierre Robin syndrome","classifications":[147,200,209]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Antenatal","Neonatal"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-06-01","source":null,"terms":[{"hpo":"HP:0001903","label":"Anemia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001541","label":"Ascites","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001789","label":"Hydrops fetalis","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001873","label":"Thrombocytopenia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000478","label":"Abnormality of the eye","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000504","label":"Abnormality of vision","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001639","label":"Hypertrophic cardiomyopathy","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0010880","label":"Increased nuchal translucency","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001511","label":"Intrauterine growth retardation","frequency":"Occasional (29-5%)","criteria":null}]}}