raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:293807

Ketamine-induced biliary dilatation

Type
Disease
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

Ketamine-induced biliary dilatation is an acquired biliary tract disease caused by the abusive consumption of ketamine, which results in the fusiform dilatation of the common bile ducts (CBD) without obstructive lesions or dilatation of the intrahepatic biliary ducts. Possible manifestations of the underlying cholangiopathy include epigastric pain and impaired liver function. Severity of CBD dilatation appears to correlate with the duration of ketamine consumption and the condition has been reported to be reversible in abstinent patients.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enKetamine-induced biliary dilatation
frDilatation des voies biliaires induite par la kétamine
deGallengangdilatation, Ketamine-induzierte
esDilatación biliar inducida por ketamina
itDilatazione biliare indotta dalla ketamina
nlKetaminegeïnduceerde galdilatatie
ptDilatação biliar induzida por quetamina
plRozszerzenie przewodów żółciowych wzbudzane ketaminą
csKetaminem indukovaná dilatace žlučových cest
ukДилатація жовчовивідних шляхів, спричинена кетаміном
zh氯胺酮诱导的胆管扩张
trKetamin-kaynaklı biliyer dilatasyon

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10X44NTBTattributedvalidated
ICD-11NE60NTBTattributedvalidated
MONDO0017394Evalidated
UMLSC4512018Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

2 records
TypeClassValueAreaQualificationValidationSource
Cases/families2 casesWorldwideCase(s)Validated22124288[PMID]
Point prevalenceUnknown—WorldwideClass onlyValidatedORPHANET_22124288[PMID]

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

4 annotations · validated 2016-10-27
HPOTerm (as annotated by Orphanet)Diagnostic
Very frequent (99-80%)
HP:0002027Abdominal pain
HP:0012440Abnormal biliary tract morphology
HP:0100518Dysuria
HP:0000738Hallucinations

Run the differential on the 4 obligate / very frequent terms

Annotation source: 22124288[PMID]

7

Sources for this card