raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:293

Congenital herpes simplex virus infection

Synonyms: Antenatal herpes simplex virus infection · Mother-to-child transmission of herpes simplex virus infection

Type
Disease
Group
Disorder
Inheritance
Not applicable
Age of onset
Antenatal, Neonatal
Status
active

Congenital herpes virus infection is a group of anomalies that an infant may present as a result of maternal infection and subsequent foetal infection with herpes virus. This virus causes recurrent cutaneous infections in adults, often involving the lips or the genitalia. Herpes infections in other organs, such as the liver or central nervous system, are less frequent.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enCongenital herpes simplex virus infectionAntenatal herpes simplex virus infection · Mother-to-child transmission of herpes simplex virus infection
frInfection congénitale à herpes simplexInfection anténatale à herpes simplex
deHerpes simplex-Virusinfektion, kongenitaleHerpes simplex-Virusinfektion durch Mutter-Kind-Übertragung · Herpesvirus-Infektion, pränatale
esInfección congénita por el virus del herpes simpleInfección prenatal por el virus del herpes simple · Transmisión materna de la infección por el virus del herpes simple
itInfezione congenita da virus dell'herpesInfezione prenatale da virus dell'herpes
nlCongenitale infectie met herpes-simplexvirusPrenatale infectie met herpes-simplexvirus · Transmissie van moeder op kind van infectie met herpes-simplexvirus
ptInfeção por herpes vírus congénitaInfeção pré-natal por herpes vírus
plWrodzone zakażenie herpeswirusowePrenatalne zakażenie herpeswirusowe
csVrozená infekce herpes viremPrenatální infekce herpes virem
ukВроджена інфекція простого герпесуАнтенатальна інфекція вірусом простого герпесу · Передача інфекції простого герпесу від матері до дитини
zh先天性单纯疱疹病毒感染母婴传播性单纯疱疹病毒感染
trDoğumsal herpes simpleks virüsü enfeksiyonuAntenatal herpes simplex virüs enfeksiyonu · Herpes simpleks virüs enfeksiyonunun anneden çocuğa bulaşması

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10P35.2NTBTattributedvalidated
ICD-111F00.YNTBTattributedvalidated
MONDO0017381Evalidated
UMLSC4275250Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (2):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

3 records
TypeClassValueAreaQualificationValidationSource
Annual incidence1-9 / 100 0006.6 / 100 000SwedenValue and classNot yet validatedORPHANET
Point prevalenceUnknown—WorldwideClass onlyNot yet validatedORPHANET
Annual incidence1-9 / 100 0001.6 / 100 000United KingdomValue and classNot yet validatedORPHANET

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

4 annotations · validated 2016-06-01
HPOTerm (as annotated by Orphanet)Diagnostic
Frequent (79-30%)
HP:0001511Intrauterine growth retardation
HP:0001622Premature birth
Occasional (29-5%)
HP:0002324Hydranencephaly
HP:0000252Microcephaly
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Sources for this card