Poliomyelitis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Childhood
- Status
- active
A rare viral infection caused by any of three serotypes of wild human poliovirus (types 1, 2 and 3), which are part of the family of enteroviruses; and three serotypes of Sabin vaccine-derived polioviruses (types 1, 2 and 3) that have accumulated genetic changes and regained the ability to cause polio paralysis. wild type 2 and type 3 polioviruses have been certified eradicated, wild type 1 poliovirus continues to circulate in Pakistan and Afghanistan, and vaccine-derived polio viruses mainly circulate in sub-Saharan Africa.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Poliomyelitis | |
| fr | Poliomyélite | |
| de | Poliomyelitis | |
| es | Poliomielitis | |
| it | Poliomielite | |
| nl | Poliomyelitis | |
| pt | Poliomielite | |
| pl | Ostre nagminne porażenie dziecięce | |
| cs | Poliomyelitida | Dětská obrna |
| uk | Поліомієліт | |
| zh | 脊髓灰质炎 | |
| tr | Çocuk felci |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A80.0 | BTNT | specific | validated |
| ICD-10 | A80.1 | BTNT | specific | validated |
| ICD-10 | A80.2 | BTNT | specific | validated |
| ICD-10 | A80.3 | BTNT | specific | validated |
| ICD-10 | A80.4 | BTNT | specific | validated |
| ICD-10 | A80.9 | BTNT | specific | validated |
| ICD-11 | 1C81 | E | specific | validated |
| MONDO | 0017373 | E | validated | |
| MeSH | D011051 | E | validated | |
| UMLS | C0032371 | E | validated | |
| GARD | 7413 | E | validated | |
| MedDRA | 10036012 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:98506Acquired motor neuron disease
rare neurological diseases - ORPHA:98010Infectious disease of the nervous system
rare neurological diseases
No children.
Codes that Orphanet moved or referred to this one:
- ORPHA:330009OBSOLETE: Poliomyelitis in patients with immunodeficiencies deemed at risk referred to · inactive
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | <1 / 1 000 000 | — | Europe | Class only | Not yet validated | ORPHANET |
| Annual incidence | <1 / 1 000 000 | — | Europe | Class only | Validated | European Centre for Disease prevention and Control 2011[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
53 annotations · validated 2020-02-28| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0001324 | Muscle weakness | |
| HP:0012531 | Pain | |
| Frequent (79-30%) | ||
| HP:0040131 | Abnormal motor nerve conduction velocity | |
| HP:0011805 | Abnormal skeletal muscle morphology | |
| HP:0002039 | Anorexia | |
| HP:0001284 | Areflexia | |
| HP:0002829 | Arthralgia | |
| HP:0001348 | Brisk reflexes | |
| HP:0003546 | Exercise intolerance | |
| HP:0012378 | Fatigue | |
| HP:0001945 | Fever | |
| HP:0004302 | Functional motor deficit | |
| HP:0002315 | Headache | |
| HP:0009004 | Hypoplasia of the musculature | |
| HP:0031469 | Low self esteem | |
| HP:0007340 | Lower limb muscle weakness | |
| HP:0001287 | Meningitis | |
| HP:0010547 | Muscle flaccidity | |
| HP:0003326 | Myalgia | |
| HP:0012486 | Myelitis | |
| HP:0002018 | Nausea | |
| HP:0003470 | Paralysis | |
| HP:0025439 | Pharyngitis | |
| HP:0003202 | Skeletal muscle atrophy | |
| HP:0025258 | Stiff neck | |
| HP:0002013 | Vomiting | |
| Occasional (29-5%) | ||
| HP:0030813 | Absent tonsils | |
| HP:0001283 | Bulbar palsy | |
| HP:0002483 | Bulbar signs | |
| HP:0006824 | Cranial nerve paralysis | |
| HP:0002374 | Diminished movement | |
| HP:0002015 | Dysphagia | |
| HP:0001618 | Dysphonia | |
| HP:0002380 | Fasciculations | |
| HP:0030196 | Fatigable weakness of respiratory muscles | |
| HP:0002487 | Hyperkinetic movements | |
| HP:0002721 | Immunodeficiency | |
| HP:0031058 | Impairment of activities of daily living | |
| HP:0002540 | Inability to walk | |
| HP:0002590 | Paralytic ileus | |
| HP:0002385 | Paraparesis | |
| HP:0003401 | Paresthesia | |
| HP:0002878 | Respiratory failure | |
| HP:0004887 | Respiratory failure requiring assisted ventilation | |
| HP:0003484 | Upper limb muscle weakness | |
| Very rare (<4-1%) | ||
| HP:0000713 | Agitation | |
| HP:0001259 | Coma | |
| HP:0001289 | Confusion | |
| HP:0000822 | Hypertension | |
| HP:0002615 | Hypotension | |
| HP:0031274 | Hypovolemic shock | |
| HP:0002383 | Infectious encephalitis | |
| HP:0000737 | Irritability | |
Run the differential on the 2 obligate / very frequent terms
Annotation source: 31690950[PMID]_8944203[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/2912
- This record as JSON: /data/d/2912.json