Paraneoplastic uveitis
- Type
- Disease
- Group
- Disorder
- Age of onset
- Adult
- Status
- active
A rare ophthalmic disorder characterized by a non-infectious uveitis potentially involving all parts of the uveal tract and due to a paraneoplastic autoimmune reaction. The signs and symptoms usually precede the tumor diagnosis and may include ocular redness and pain, light sensitivity, blurred vision, floaters, and decreased vision. The most classic form is the intermediate uveitis associated with anti-CV2 antibodies in small-cell lung cancer or other neoplasms. Other ocular and/or extra-ocular manifestations are commonly present in addition.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Paraneoplastic uveitis | |
| fr | Uvéite paranéoplasique | |
| de | Uveitis, paraneoplastische | |
| es | Uveítis paraneoplásica | |
| it | Uveite paraneoplastica | |
| nl | Paraneoplastische uveïtis | |
| pt | Uveíte paraneoplásica | |
| pl | Paraneoplastyczne zapalenie błony naczyniowej oka | |
| cs | Paraneoplastická uveitida | |
| uk | Паранеопластичний увеїт | |
| zh | 副肿瘤性葡萄膜炎 | |
| tr | Paraneoplastik üveit |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | H57.8 | NTBT | attributed | validated |
| ICD-11 | 9B65.0 | NTBT | attributed | validated |
| MONDO | 0017212 | E | validated | |
| UMLS | C5680786 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:90061Non-infectious posterior uveitis
rare ophthalmic disorders
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Cases/families | 10 cases | Worldwide | Case(s) | Validated | 41003888[PMID] | |
| Point prevalence | <1 / 1 000 000 | — | Worldwide | Class only | Validated | 41003888[PMID]_ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/279928
- This record as JSON: /data/d/279928.json