raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:264978

Drug or radiation exposure-related interstitial lung disease

Type
Particular clinical situation in a disease or syndrome
Group
Disorder
Age of onset
All ages
Status
active

A rare secondary interstitial lung disease (ILD) characterized by development of the condition after exposure to certain drugs or radiation therapy. Diagnostic criteria include clear temporal association, identification of a characteristic reaction pattern to the respective drug, and exclusion of other causes of the ILD. Clinically, drug-induced ILD (DI-ILD) may occur as acute ILD with respiratory failure, or as subacute/chronic DI-ILD. Radiation injury to the lung can develop during or following radiation therapy and depends on the nature and dose of the ionizing radiation, as well as the direction of the radiation beam.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enDrug or radiation exposure-related interstitial lung disease
frPneumopathie interstitielle médicamenteuse ou secondaire à une exposition aux radiations
deInterstitielle Lungenkrankheit, Substanz- oder Strahleninduzierte
esEnfermedad pulmonar intersticial asociada a la exposición a fármacos o radiación
itPneumopatia interstiziale da farmaci o esposizione a radiazioni
nlInterstitiële longziekte gerelateerd aan medicatie of radiatie
ptDoença pulmonar intersticial relacionada com exposição a fármacos ou radiação
plŚródmiąższowa choroba płuc zwiaząna z ekspozycją na leki lub promieniowanie
csIntersticiální plicní nemoc související s expozicí lékům a radiaci
ukІнтерстиціальна хвороба легень, повязана з медикаментозним або радіаційним впливом
zh药物或辐射相关间质性肺病
trİlaç veya radyasyona maruz kalma nedeniyle interstisyel akciğer hastalığı

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10J70.2BTNTattributedvalidated
ICD-10J70.3BTNTattributedvalidated
ICD-10J70.4BTNTattributedvalidated
ICD-11CB0YNTBTattributedvalidated
MONDO0017039Evalidated
UMLSC5680746Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

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Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

1 record
TypeClassValueAreaQualificationValidationSource
Point prevalenceUnknown—WorldwideClass onlyNot yet validatedORPHANET

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

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HPO phenotypes

Orphanet has no HPO annotation for this code in this release.

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Sources for this card