ORPHA:251656
Oligoastrocytoma, dual genotype
Synonyms: MOA · Mixed oligoastrocytoma · Oligoastrocytoma, dual genotype NEC · Oligoastrocytoma, dual genotype, not elsewhere classified
- Type
- Disease
- Group
- Disorder
- Status
- active
Oligoastrocytoma is a type of low-grade glioma with a mixed astrocytoma and oligodendroglioma histology, manifesting with headaches, speech and motor problems, seizures and, in some, subarachnoid haemorrhage.
1
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Oligoastrocytoma, dual genotype | MOA · Mixed oligoastrocytoma · Oligoastrocytoma, dual genotype NEC · Oligoastrocytoma, dual genotype, not elsewhere classified |
| fr | Oligoastrocytome, génotype hybride | MOA · Oligoastrocytome mixte · Oligoastrocytome, génotype hybride NEC · Oligoastrocytome, génotype hybride not elsewhere classified |
| de | Oligoastrozytom mit dualem Genotyp | MOA · Oligoastrozytom, gemischtes · Oligoastrozytom mit doppeltem Genotyp, andernorts nicht klassifiziert |
| es | Oligoastrocitoma de genotipo dual | MOA · Oligoastrocitoma mixto · Oligoastrocitoma, genotipo dual, no clasificado en otra parte |
| it | Oligoastrocitoma, genotipo ibrido | MOA · Oligoastrocitoma misto · Oligoastrocitoma, genotipo ibrido NEC · Oligoastrocitoma, genotipo ibrido, non classificato diversamente |
| nl | Oligoastrocytoom, duaal genotype | Gemengd oligoastrocytoom · MOA · Oligoastrocytoom, duaal genotype NEC · Oligoastrocytoom, duaal genotype, niet elders geclassificeerd |
| pt | Oligoastrocitoma | MOA · Oligoastrocitoma misto |
| pl | Skąpodrzewiakogwiaździak | MOA · Skąpodrzewiakogwiaździak mieszany |
| cs | Oligoastrocytom | MOA · Smíšený oligoastrocytom |
| uk | Олігоастроцитома | Змішана олігоастроцитома · MOA |
| zh | 少突星形细胞瘤 | 少突星形细胞混合瘤 |
| tr | Oligoastrositom | MOA · Karma oligoastrositom |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | C71.9 | NTBT | index | validated |
| ICD-11 | 2A00.0Y | NTBT | index | validated |
| MONDO | 0016702 | E | validated | |
| UMLS | C0547065 | E | validated | |
| GARD | 9769 | E | validated | |
| MedDRA | 10073131 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
3
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:251651Oligoastrocytic tumor
rare neurological diseases; rare neoplastic diseases
No children.
4
Genes
1 direct| Gene | Association | Status | HGNC | Ensembl | OMIM | Locus | Name | Source of validation |
|---|---|---|---|---|---|---|---|---|
| IDH2 | Biomarker tested in | Assessed | HGNC:5383 | ENSG00000182054 | 147650 | 15q26.1 | isocitrate dehydrogenase (NADP(+)) 2 | 19228619[PMID]_19554337[PMID]_23109653[PMID]_24149775[PMID]_20714900[PMID]_21075857[PMID] |
5
Prevalence and incidence
0 recordsNo prevalence record in this release.
6
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
7
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/251656
- This record as JSON: /data/d/251656.json