Inflammatory myopathy with abundant macrophages
Synonyms: IMAM
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Status
- active
A rare idiopathic inflammatory myopathy characterized by diffuse destructive infiltration of CD68+ macrophages into the fascia rather than muscle fibers in muscle biopsies, proximal muscle weakness and myalgia with or without scaly dermatomyositis-like or atypical non-dermatomyositis-like skin lesions, elevation of creatine kinase levels and thickening of muscle fascia in muscle MRI.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Inflammatory myopathy with abundant macrophages | IMAM |
| fr | Myopathie inflammatoire avec abondance de macrophages | IMAM · MIAM |
| de | Inflammatorische Myopathie mit überzähligen Makrophagen | = en |
| es | Miopatía inflamatoria con abundancia de macrófagos | = en |
| it | Miopatia infiammatoria con eccesso di macrofagi | = en |
| nl | Inflammatoire myopathie met abundante macrofagen | = en |
| pt | Miopatia inflamatória com macrófagos abundantes | |
| pl | Miopatia zapalna z licznymi makrofagami | = en |
| cs | Zánětlivá myopatie s nadbytkem makrofágů | = en |
| uk | Запальна міопатія з великою кількістю макрофагів | ІМАМ |
| zh | 炎症型肌病伴大量巨噬细胞 | = en |
| tr | Bol makrofajlar ile seyreden inflamatuar miyopati | = en |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G72.4 | NTBT | attributed | validated |
| MONDO | 0016609 | E | validated | |
| UMLS | C4707791 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:98482Idiopathic inflammatory myopathy
rare neurological diseases; rare systemic and rheumatological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
0 recordsNo prevalence record in this release.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/247718
- This record as JSON: /data/d/247718.json