Inhalational anthrax
Synonyms: Inhalation anthrax disease · Pulmonary anthrax · Respiratory anthrax · Respiratory anthrax disease
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
Inhalational anthrax is a rare acute systemic infection caused by the inhalation of <i>Bacillus anthracis</i> spores (e.g. through infected animal products, bioterrorism) and characterized by an initial stage where patients present with non specific symptoms (fever, cough, chills, fatigue) that is followed by an acute phase during which hemorrhagic mediastinitis occurs that can progress into meningitis, gastrointestinal involvement, and refractory shock, that can be fatal, if left untreated.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Inhalational anthrax | Inhalation anthrax disease · Pulmonary anthrax · Respiratory anthrax · Respiratory anthrax disease |
| fr | Charbon pulmonaire | Maladie du charbon, forme respiratoire · Maladie du charbon, forme par inhalation |
| de | Anthrax durch Inhalation | Lungenmilzbrand |
| es | Enfermedad por inhalación de ántrax | Enfermedad respiratoria por inhalación de ántrax |
| it | Malattia da inalazione di antrace | Malattia respiratoria da antrace |
| nl | Inhalatie-anthrax | Inhalatie-anthraxziekte · Pulmonale anthrax · Respiratoire anthrax · Respiratoire anthraxziekte |
| pt | Doença por inalação de antrax | |
| pl | Wąglik płucny | Wąglik oddechowy · Wąglik płucny |
| cs | Inhalační antrax | Plicní antrax · Respirační antrax |
| uk | Інгаляційна сибірська виразка | Інгаляційна форма сибірської виразки · Легенева форма сибірської виразки · Респіраторна сибірська виразка · Респіраторна форма сибірської виразки |
| zh | 吸入性炭疽病 | 吸入性炭疽病 |
| tr | Solunum yoluyla alınan şarbon | Pulmoner şarbon · Solunum şarbonu · İnhalasyon şarbon hastalığı · Solunum şarbon hastalığı |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A22.1 | NTBT | attributed | validated |
| ICD-11 | 1B97 | NTBT | index | validated |
| MONDO | 0016595 | E | validated | |
| MeSH | C571912 | E | validated | |
| UMLS | C0155866 | E | validated | |
| MedDRA | 10035667 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163582Rare bacterial infectious disease
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | <1 / 1 000 000 | — | Europe | Class only | Validated | European Medicines Agency 2018[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
12 annotations · validated 2017-04-03| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0000971 | Abnormality of the sweat gland | |
| HP:0011159 | Epigastric auras | |
| HP:0012378 | Fatigue | |
| HP:0001945 | Fever | |
| Frequent (79-30%) | ||
| HP:0001289 | Confusion | |
| HP:0002094 | Dyspnea | |
| HP:0002615 | Hypotension | |
| HP:0002546 | Incomprehensible speech | |
| HP:0011029 | Internal hemorrhage | |
| HP:0002098 | Respiratory distress | |
| HP:0100806 | Sepsis | |
| HP:0002013 | Vomiting | |
Run the differential on the 4 obligate / very frequent terms
Annotation source: 10559102[PMID]_12396910[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/247257
- This record as JSON: /data/d/247257.json