Loiasis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
Loiasis is a form of filariasis, caused by the parasitic worm <i>Loa loa</i>, endemic to the forest and savannah regions of Central and Western Africa. Loiasis may either be asymptomatic or manifest as a large, transient area of localized, non-erythematous subcutaneous edema (Calabar swellings), adult worm migration through the sub-conjunctiva (''African eye worm'') and pruritus. Generalized itching, hives, muscle pains, arthralgias, fatigue, and adult worms visibly migrating under the surface of the skin may be observed. Severe complications such as encephalopathy have been reported in highly infected individuals receiving ivermectin during mass drug administration programs for the control of onchocerciasis and lymphatic filariasis.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Loiasis | |
| fr | Loase | Filariose à loa-loa · Loaose |
| de | Loiasis | Afrikanischer Augenwurm |
| es | Loasis | |
| it | Loiasi | |
| nl | Loiasis | |
| pt | Loiasiose | |
| pl | Loaoza | |
| cs | Loaiáza | Loalóza · Loaóza |
| uk | Лоіазіс | |
| zh | 罗阿丝虫病 | |
| tr | Loiasis |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | B74.3 | E | specific | validated |
| ICD-11 | 1F66.0 | E | specific | validated |
| MONDO | 0016566 | E | validated | |
| MeSH | D008118 | E | validated | |
| UMLS | C0023968 | E | validated | |
| GARD | 3283 | E | validated | |
| MedDRA | 10024797 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:2034Filariasis
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | <1 / 1 000 000 | — | Europe | Class only | Validated | 22784545[PMID] |
| Point prevalence | >1 / 1000 | — | Specific population | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/2404
- This record as JSON: /data/d/2404.json