Asbestos intoxication
Synonyms: Asbestosis
- Type
- Disease
- Group
- Disorder
- Age of onset
- All ages
- Status
- active
A rare pneumoconiosis caused by exposure to asbestos particles. Symptoms may appear many years after exposure and include progressive dyspnea on exertion, dry cough, chest pain, tightness, inspiratory crackles, clubbing of the fingers. Later complications include mesothelioma and lung cancers.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Asbestos intoxication | Asbestosis |
| fr | Intoxication à l'amiante | Asbestose |
| de | Asbestintoxifikation | Asbestose |
| es | Intoxicación por amianto | = en |
| it | Intossicazione da asbesto | |
| nl | Asbestintoxicatie | Asbestose |
| pt | Intoxicação por amianto | Asbestose |
| pl | Zatrucie azbestem | Pylica azbestowa |
| cs | Intoxikace azbestem | Azbestóza |
| uk | Азбестова інтоксикація | Азбестоз |
| zh | 石棉中毒 | 石棉肺 |
| tr | Asbest zehirlenmesi | Asbestoz |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | J61 | NTBT | inclusion | validated |
| ICD-11 | CA60.2 | E | specific | validated |
| MONDO | 0016466 | E | validated | |
| MeSH | D001195 | E | validated | |
| UMLS | C0003949 | E | validated | |
| GARD | 5852 | E | validated | |
| MedDRA | 10003441 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:182098Pneumoconiosis
rare respiratory diseases; rare transplant-related disorders
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
35 annotations · validated 2020-12-04| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Frequent (79-30%) | ||
| HP:0006530 | Abnormal pulmonary interstitial morphology | |
| HP:0002086 | Abnormality of the respiratory system | |
| HP:0045051 | Decreased DLCO | |
| HP:0002207 | Diffuse reticular or finely nodular infiltrations | |
| HP:0002094 | Dyspnea | |
| HP:0003546 | Exercise intolerance | |
| HP:0002875 | Exertional dyspnea | |
| HP:0031998 | Late inspiratory crackles | |
| HP:0031246 | Nonproductive cough | |
| HP:0030874 | Oxygen desaturation on exertion | |
| HP:0031944 | Pleural thickening | |
| HP:0032341 | Reduced forced vital capacity | |
| HP:0002792 | Reduced vital capacity | |
| HP:0002091 | Restrictive ventilatory defect | |
| HP:0031631 | Subpleural honeycombing | |
| Occasional (29-5%) | ||
| HP:0032016 | Abnormal sputum | |
| HP:0100749 | Chest pain | |
| HP:0031352 | Chest tightness | |
| HP:0100759 | Clubbing of fingers | |
| HP:0001648 | Cor pulmonale | |
| HP:0000961 | Cyanosis | |
| HP:0025179 | Ground-glass opacification on pulmonary HRCT | |
| HP:0030849 | Hepatojugular reflux | |
| HP:0012418 | Hypoxemia | |
| HP:0030879 | Interlobular septal thickening on pulmonary HRCT | |
| HP:0002206 | Pulmonary fibrosis | |
| HP:0002878 | Respiratory failure | |
| HP:0001708 | Right ventricular failure | |
| HP:0030828 | Wheezing | |
| Very rare (<4-1%) | ||
| HP:0100750 | Atelectasis | |
| HP:0000969 | Edema | |
| HP:0030078 | Lung adenocarcinoma | |
| HP:0100001 | Malignant mesothelioma | |
| HP:0100721 | Mediastinal lymphadenopathy | |
| HP:0001685 | Myocardial fibrosis | |
Annotation source: 9012357[PMID]_21281828[PMID]_30753424[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/2302
- This record as JSON: /data/d/2302.json