ORPHA:228123
Coccidioidomycosis
Synonyms: Desert rheumatism · San Joaquin valley fever · Valley fever · California disease · Coccidioides infection · Desert fever
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
Coccidioidomycosis is a fungal infection caused by <i>Coccidioides immitis</i> and <i>C. posadasii</i>, which is endemic to the Southwestern United States, Central America, South America and Mexico, and is acquired by inhalation of the infective arthroconidia, often found in soil. In most cases it is a benign, self-limiting febrile illness, but in a minority of cases it can become a potentially lethal infection of the lungs and, extremely rarely, spread to other organs (through hematogenous dissemination) with manifestations including meningitis, osteomyelitis, and skin and soft-tissue involvement.
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Coccidioidomycosis | Desert rheumatism · San Joaquin valley fever · Valley fever · California disease · Coccidioides infection · Desert fever |
| fr | Coccidioïdomycose | Fièvre de la vallée · Fièvre de la vallée de Californie · Fièvre de la vallée de San Joaquin · Fièvre du désert · Maladie de Californie · Rhumatisme du désert |
| de | Kokzidioidomykose | Coccidioides-Infektion · Talfieber · Valley-Fieber · Wüstenfieber · Wüstenrheumatismus |
| es | Coccidioidomicosis | Enfermedad de California · Fiebre del Valle · Fiebre del desierto · Fiebre del valle de San Joaquín · Infección por Coccidioides · Reumatismo del desierto |
| it | Coccidioidomicosi | Febbre del deserto · Febbre della valle · Febbre della valle di San Joaquin · Infezione da Coccidioides · Malattia della California · Reumatismo del deserto |
| nl | Coccidioïdomycose | California ziekte · Coccidioïdesinfectie · San Joaquin valleikoorts · Valleikoorts · Woestijnkoorts · Woestijnreuma |
| pt | Coccidioidomicose | |
| pl | Kokcydioidomikoza | Choroba Kalifornijska · Goraczka pustynna · Reumatyzm pustynny · Valley fever |
| cs | Kokcidiomykóza | Kalifornská nemoc · Kokcidiová infekce · Pouštní revmatismus · Pouštní horečka · Horečka údolí San Joaquin · Údolní horečka |
| uk | Кокцидіоїдомікоз | Каліфорнійська хвороба · Кокцидіозна інфекція · Лихоманка пустелі · Пустельний ревматизм · Лихоманка долини Сан-Хоакін · Лихоманка долини |
| zh | 球孢子菌病 | 球孢子菌感染 |
| tr | Koksidioidomikoz | Çöl ateşi · Vadi ateşi · Çöl romatizması · California hastalığı · Koksidfoid enfeksiyonu · San Joaquin vadisi ateşi |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | B38.0 | BTNT | specific | validated |
| ICD-10 | B38.1 | BTNT | specific | validated |
| ICD-10 | B38.2 | BTNT | specific | validated |
| ICD-10 | B38.3 | BTNT | specific | validated |
| ICD-10 | B38.4 | BTNT | specific | validated |
| ICD-10 | B38.7 | BTNT | specific | validated |
| ICD-10 | B38.8 | BTNT | specific | validated |
| ICD-10 | B38.9 | BTNT | specific | validated |
| ICD-11 | 1F25 | E | specific | validated |
| ICD-11 | 1F25.0 | BTNT | specific | validated |
| ICD-11 | 1F25.00 | BTNT | specific | validated |
| ICD-11 | 1F25.01 | BTNT | specific | validated |
| ICD-11 | 1F25.1 | BTNT | specific | validated |
| ICD-11 | 1F25.10 | BTNT | specific | validated |
| ICD-11 | 1F25.11 | BTNT | specific | validated |
| ICD-11 | 1F25.12 | BTNT | specific | validated |
| ICD-11 | 1F25.1Y | BTNT | attributed | validated |
| MONDO | 0005706 | E | validated | |
| MeSH | D003047 | E | validated | |
| UMLS | C0009186 | E | validated | |
| GARD | 9525 | E | validated | |
| MedDRA | 10009825 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163591Rare mycosis
rare infectious diseases
No children.
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
76 annotations · validated 2020-04-23| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Frequent (79-30%) | ||
| HP:0001945 | Fever | |
| HP:0002721 | Immunodeficiency | |
| HP:0003237 | Increased circulating IgG level | |
| HP:0003496 | Increased circulating IgM level | |
| HP:0002090 | Pneumonia | |
| Occasional (29-5%) | ||
| HP:0000707 | Abnormality of the nervous system | |
| HP:0025615 | Abscess | |
| HP:0001369 | Arthritis | |
| HP:0000987 | Atypical scarring of skin | |
| HP:0200149 | CSF lymphocytic pleiocytosis | |
| HP:0012229 | CSF pleocytosis | |
| HP:0100749 | Chest pain | |
| HP:0012735 | Cough | |
| HP:0012219 | Erythema nodosum | |
| HP:0011921 | Exudative pleural effusion | |
| HP:0012378 | Fatigue | |
| HP:0025084 | Folliculitis | |
| HP:0032252 | Granuloma | |
| HP:0002105 | Hemoptysis | |
| HP:0011972 | Hypoglycorrhachia | |
| HP:0002922 | Increased CSF protein concentration | |
| HP:0001880 | Increased total eosinophil count | |
| HP:0032217 | Indurated nodule | |
| HP:0002716 | Lymphadenopathy | |
| HP:0100721 | Mediastinal lymphadenopathy | |
| HP:0012282 | Morbilliform rash | |
| HP:0003326 | Myalgia | |
| HP:0012490 | Panniculitis | |
| HP:0200034 | Papule | |
| HP:0032177 | Parenchymal consolidation | |
| HP:0011919 | Pleural empyema | |
| HP:0000989 | Pruritus | |
| HP:0002113 | Pulmonary infiltrates | |
| HP:0002098 | Respiratory distress | |
| HP:0200035 | Skin plaque | |
| HP:0000988 | Skin rash | |
| HP:0011450 | Unusual CNS infection | |
| HP:0030351 | Urticarial plaque | |
| HP:0012500 | Verrucous papule | |
| Very rare (<4-1%) | ||
| HP:0005916 | Abnormal metacarpal morphology | |
| HP:0000479 | Abnormal retinal morphology | |
| HP:0012864 | Abnormal sperm morphology | |
| HP:0001871 | Abnormality of blood and blood-forming tissues | |
| HP:0011314 | Abnormality of long bone morphology | |
| HP:0000014 | Abnormality of the bladder | |
| HP:0000818 | Abnormality of the endocrine system | |
| HP:0010460 | Abnormality of the female genitalia | |
| HP:0000119 | Abnormality of the genitourinary system | |
| HP:0000077 | Abnormality of the kidney | |
| HP:0001392 | Abnormality of the liver | |
| HP:0010461 | Abnormality of the male genitalia | |
| HP:0001743 | Abnormality of the spleen | |
| HP:0000925 | Abnormality of the vertebral column | |
| HP:0000622 | Blurred vision | |
| HP:0001783 | Broad metatarsal | |
| HP:0000885 | Broad ribs | |
| HP:0002682 | Broad skull | |
| HP:0002637 | Cerebral ischemia | |
| HP:0032161 | Coccidioidal meningitis | |
| HP:0100543 | Cognitive impairment | |
| HP:0002315 | Headache | |
| HP:0000365 | Hearing impairment | |
| HP:0000238 | Hydrocephalus | |
| HP:0020101 | Invasive fungal infection | |
| HP:0031179 | Nuchal rigidity | |
| HP:0002797 | Osteolysis | |
| HP:0002754 | Osteomyelitis | |
| HP:0001733 | Pancreatitis | |
| HP:0001701 | Pericarditis | |
| HP:0002586 | Peritonitis | |
| HP:0000751 | Personality changes | |
| HP:0000613 | Photophobia | |
| HP:0000083 | Renal insufficiency | |
| HP:0001250 | Seizure | |
| HP:0002633 | Vasculitis | |
| HP:0025637 | Vasospasm | |
Annotation source: 26739609[PMID]_30690606[PMID]_23068145[PMID]
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/228123
- This record as JSON: /data/d/228123.json