Glossopharyngeal neuralgia
- Type
- Disease
- Group
- Disorder
- Age of onset
- Adolescent, Adult, Elderly
- Status
- active
A rare cranial neuralgia characterized by paroxysmal, usually unilateral stabbing pain within the sensory distributions of the auricular and pharyngeal branches of the glossopharyngeal and sometimes the vagus nerve (i. e. the posterior part of the tongue, the tonsillar fossa, oropharynx, larynx, angle of the mandible, and/or ear). The attacks last seconds to minutes with intervals between the paroxysms ranging from a few minutes to a few hours, and appear in clusters lasting weeks to months, again with irregular intervals in between. Pain attacks are usually triggered by a specific stimulus but may also occur spontaneously. The condition can sometimes be associated with bradycardia, syncope, seizures, and even asystole, and is then termed vagoglossopharyngeal neuralgia.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Glossopharyngeal neuralgia | |
| fr | Névralgie glossopharyngienne | Névralgie du glossopharyngien · Névralgie glossopharyngée |
| de | Glossopharyngeusneuralgie | |
| es | Neuralgia glosofaríngea | |
| it | Nevralgia glossofaringea | Nevralgia glosso-vaso-faringea |
| nl | Glossofaryngeale neuralgie | Neuralgie van nervus glossopharyngeus |
| pt | Neuralgia glossofaríngea | |
| pl | Neuralgia nerwu językowo-gardłowego | Neuralgia językowo-błędno-gardłowa |
| cs | Glossofaryngeální neuralgie | Glossovasofaryngeální neuralgie |
| uk | Невралгія глоткового нерва | |
| zh | 舌咽神经痛 | |
| tr | Glossofarengeal nevralji |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G52.1 | NTBT | inclusion | validated |
| ICD-11 | 8B87 | NTBT | index | validated |
| MONDO | 0016372 | E | validated | |
| MeSH | D020435 | E | validated | |
| UMLS | C0154731 | E | validated | |
| GARD | 6519 | E | validated | |
| MedDRA | 10018391 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:221109Cranial neuralgia
rare neurological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | ORPHANET |
| Annual incidence | 1-9 / 1 000 000 | 0.7 / 100 000 | United States | Value and class | Validated | 1798430[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
28 annotations · validated 2021-03-23| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Frequent (79-30%) | ||
| HP:3000047 | Abnormal glossopharyngeal nerve morphology | |
| HP:0000739 | Anxiety | |
| HP:0001293 | Cranial nerve compression | |
| HP:0000716 | Depression | |
| HP:0030766 | Ear pain | |
| HP:0032148 | Episodic pain | |
| HP:0030164 | Jaw claudication | |
| HP:0200025 | Mandibular pain | |
| HP:0030811 | Tongue pain | |
| Occasional (29-5%) | ||
| HP:0000174 | Abnormal palate morphology | |
| HP:0003319 | Abnormality of the cervical spine | |
| HP:0002960 | Autoimmunity | |
| HP:0001662 | Bradycardia | |
| HP:0007099 | Chiari type I malformation | |
| HP:0002617 | Dilatation | |
| HP:0012534 | Dysesthesia | |
| HP:0011968 | Feeding difficulties | |
| HP:0002315 | Headache | |
| HP:0001609 | Hoarse voice | |
| HP:0004395 | Malnutrition | |
| HP:0002664 | Neoplasm | |
| HP:0032043 | Odynophagia | |
| HP:0200136 | Oral-pharyngeal dysphagia | |
| HP:0100008 | Schwannoma | |
| HP:0001250 | Seizure | |
| HP:0001279 | Syncope | |
| HP:0001605 | Vocal cord paralysis | |
| HP:0001824 | Weight loss | |
Annotation source: 30361762[PMID]_31082085[PMID]_28827979[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/221098
- This record as JSON: /data/d/221098.json