raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:210272

Mal de débarquement

Synonyms: Disembarkment syndrome · MdD · MdDS · Sickness of disembarkment

Type
Clinical syndrome
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

Mal de débarquement (MdD) is a rare otorhinolaryngological disease characterized by a persistent sensation of motion such as rocking, swaying, tumbling and/or bobbing following a period of exposure to passive movement, usually an ocean cruise or other types of water, train, automobile or air travel and less commonly other movements (like sleeping on a waterbed). Onset may be spontaneous in some patients. Manifestations begin shortly after the stimulus, persist for 6 months to years and may be associated with anxiety, fatigue and impaired cognition. Symptoms are often accentuated when in an enclosed space or when attempting to be motionless (sitting, lying down or standing in a stationary position) and are relieved when in passive motion such as in a moving car, airplane or train.

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Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enMal de débarquementDisembarkment syndrome · MdD · MdDS · Sickness of disembarkment
frMal de débarquementMdD
deMal-de-Débarquement-SyndromLandkrankheit · MdD · MdDS
esEnfermedad del desembarcoSíndrome 'mal de débarquement' · Síndrome del desembarco · MdD · MdDS
itMal de débarquementMalattia dello sbarco · Malessere dello sbarco · MdD · MdDS · Sindrome "mal de debarquement" · Sindrome "mal de débarquement" · Sindrome dello sbarco
nlMal de débarquementMal de débarquement-syndroom · MdD · MdDS · Ontschepingssyndroom · Ziekte van de ontscheping
ptDoença de desembarque
plChoroba "zejścia na lądMdD · MdDS · Zespół "zejścia na ląd · Zespół "zejścia na ląd
csNemoc z vyloděníMDD · MdDS · Syndrom vylodění
ukMal de débarquementСиндром висадки · MdD · MdDS · Хвороба висадки
zh上岸综合征上岸疾病
trMal de dèbarquementMdD · MdDS · Disembarkment sendromu · Disembarkment hastalığı

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10H81.8NTBTattributedvalidated
ICD-11AB31.4Especificvalidated
MONDO0016217Evalidated
MeSHC537840Evalidated
UMLSC1608983Evalidated
GARD6959Evalidated
MedDRA10064924Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

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Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

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Prevalence and incidence

1 record
TypeClassValueAreaQualificationValidationSource
Point prevalenceUnknown—WorldwideClass onlyValidatedORPHANET

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

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HPO phenotypes

17 annotations · validated 2021-03-18
HPOTerm (as annotated by Orphanet)Diagnostic
Frequent (79-30%)
HP:0002141Gait imbalance
HP:0002172Postural instability
HP:0002317Unsteady gait
HP:0002321Vertigo
Occasional (29-5%)
HP:0000496Abnormality of eye movement
HP:0000739Anxiety
HP:0000622Blurred vision
HP:0001289Confusion
HP:0000651Diplopia
HP:0030826Eyelid fasciculation
HP:0012378Fatigue
HP:0002315Headache
HP:0002076Migraine
HP:0002018Nausea
HP:0002013Vomiting
Excluded (0%)
HP:0007670Abnormal vestibulo-ocular reflex
HP:0410263Brain imaging abnormality

Annotation source: 32986636[PMID]_31580016[PMID]_26559820[PMID]

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Sources for this card