{"orpha":210272,"name":"Mal de débarquement","type":"Clinical syndrome","group":"Disorder","status":"active","flags":[],"synonyms":["Disembarkment syndrome","MdD","MdDS","Sickness of disembarkment"],"definition":"Mal de débarquement (MdD) is a rare otorhinolaryngological disease characterized by a persistent sensation of motion such as rocking, swaying, tumbling and/or bobbing following a period of exposure to passive movement, usually an ocean cruise or other types of water, train, automobile or air travel and less commonly other movements (like sleeping on a waterbed). Onset may be spontaneous in some patients. Manifestations begin shortly after the stimulus, persist for 6 months to years and may be associated with anxiety, fatigue and impaired cognition. Symptoms are often accentuated when in an enclosed space or when attempting to be motionless (sitting, lying down or standing in a stationary position) and are relieved when in passive motion such as in a moving car, airplane or train.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-210272/","orphanet_url":"https://www.orpha.net/en/disease/detail/210272","names":{"fr":{"name":"Mal de débarquement","synonyms":["MdD"],"definition":"Maladie otorhinolaryngologique rare caractérisée par une sensation persistante de mouvement à type de balancement, d'oscillation, de rebondissement et/ou de flottement survenant à la suite d'une exposition à un mouvement passif, généralement une croisière en mer ou d'autres types de voyages sur l'eau, en train, en voiture ou en avion, et plus rarement à d'autres mouvements (comme celui de dormir sur un matelas à eau). L'apparition peut être spontanée chez certains patients. Les manifestations commencent peu après le stimulus, persistent entre 6 mois et plusieurs années et peuvent être associées à de l'anxiété, de la fatigue et à des troubles cognitifs. Les symptômes sont souvent accentués dans un espace clos ou lorsque l'on essaie de rester immobile (assis, couché ou debout dans une position stationnaire) et s'atténuent lors d'un mouvement passif, par exemple dans une voiture, un avion ou dans un train en mouvement."},"de":{"name":"Mal-de-Débarquement-Syndrom","synonyms":["Landkrankheit","MdD","MdDS"]},"es":{"name":"Enfermedad del desembarco","synonyms":["Síndrome 'mal de débarquement'","Síndrome del desembarco","MdD","MdDS"],"definition":"Es una enfermedad otorrinolaringológica poco frecuente caracterizada por una sensación persistente de movimiento, como mecerse, balancearse y/o dar vueltas después de un período de exposición al movimiento pasivo, generalmente un crucero marítimo o de otro tipo, desplazamientos en tren, automóvil o avión y, con menor frecuencia, otros movimientos (como dormir en una cama de agua). El inicio puede ser espontáneo en algunos pacientes. Las manifestaciones comienzan poco después del estímulo, persisten durante 6 meses a años y pueden estar asociadas con ansiedad, cansancio y afectación cognitiva. Los síntomas se suelen acentuar en espacios cerrados o cuando se intenta estar inmóvil (sentado, acostado o de pie en una posición estacionaria) y se alivian cuando se está en movimiento pasivo, como en un automóvil, avión o tren en marcha."},"it":{"name":"Mal de débarquement","synonyms":["Malattia dello sbarco","Malessere dello sbarco","MdD","MdDS","Sindrome \"mal de debarquement\"","Sindrome \"mal de débarquement\"","Sindrome dello sbarco"]},"nl":{"name":"Mal de débarquement","synonyms":["Mal de débarquement-syndroom","MdD","MdDS","Ontschepingssyndroom","Ziekte van de ontscheping"],"definition":"Mal de débarquement (MdD) is een zeldzame otorinolaryngologische ziekte die wordt gekarakteriseerd door een aanhoudend gevoel van beweging zoals wiegen, wiebelen, tuimelen en/of huppelen na een periode van passief bewegen, meestal een rondvaart op de oceaan of andere soorten water, of een reis met een trein, auto of vliegtuig, maar soms ook andere bewegingen (zoals slapen op een waterbed). De aanvang kan spontaan optreden bij sommige patiënten. De manifestaties starten kort na de stimulus, houden 6 maanden tot jaren aan en kunnen geassocieerd zijn met angst, vermoeidheid en verstoorde cognitie. Symptomen zijn vaak nadrukkelijker aanwezig in een gesloten ruimte of wanneer men bewegingsloos probeert te zijn (zitten, neerliggen of staan in een stilstaande positie) en worden verlicht bij passieve beweging zoals in een auto, vliegtuig of trein in beweging."},"pt":{"name":"Doença de desembarque"},"pl":{"name":"Choroba \"zejścia na ląd","synonyms":["MdD","MdDS","Zespół \"zejścia na ląd","Zespół \"zejścia na ląd"]},"cs":{"name":"Nemoc z vylodění","synonyms":["MDD","MdDS","Syndrom vylodění"]},"uk":{"name":"Mal de débarquement","synonyms":["Синдром висадки","MdD","MdDS","Хвороба висадки"],"definition":"Mal de débarquement (MdD) is a rare otorhinolaryngological disease characterized by a persistent sensation of motion such as rocking, swaying, tumbling and/or bobbing following a period of exposure to passive movement, usually an ocean cruise or other types of water, train, automobile or air travel and less commonly other movements (like sleeping on a waterbed). Onset may be spontaneous in some patients. Manifestations begin shortly after the stimulus, persist for 6 months to years and may be associated with anxiety, fatigue and impaired cognition. Symptoms are often accentuated when in an enclosed space or when attempting to be motionless (sitting, lying down or standing in a stationary position) and are relieved when in passive motion such as in a moving car, airplane or train."},"zh":{"name":"上岸综合征","synonyms":["上岸疾病"],"definition":"上岸综合征 (MdD)是一种罕见的耳鼻喉科疾病,其主要临床表现为被动运动的一段时间内持续有运动的感觉，如摇晃，摇摆，翻滚和（或）摆动，通常是在邮轮、火车、汽车、飞机等海陆空交通工具上或其他不常见的移动(如睡在水床上)。部分患者可自发性起病，在刺激后短时间内就出现症状，持续6个月到数年，与焦虑、疲劳和认知障碍有关。在封闭环境或静止(坐着、躺着或以静止姿势站立)时，症状往往加重，而在被动运动时，如在移动的汽车、飞机或火车上，症状会缓解。"},"tr":{"name":"Mal de dèbarquement","synonyms":["MdD","MdDS","Disembarkment sendromu","Disembarkment hastalığı"]}},"xrefs":[{"source":"ICD-10","code":"H81.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"AB31.4","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"459420954"},{"source":"MONDO","code":"0016217","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"C537840","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1608983","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"6959","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10064924","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98036,"name":"Rare otorhinolaryngologic disease"},"parents":[{"orpha":98036,"name":"Rare otorhinolaryngologic disease","classifications":[200]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2021-03-18","source":"32986636[PMID]_31580016[PMID]_26559820[PMID]","terms":[{"hpo":"HP:0002141","label":"Gait imbalance","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002172","label":"Postural instability","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002317","label":"Unsteady gait","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002321","label":"Vertigo","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000496","label":"Abnormality of eye movement","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000739","label":"Anxiety","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000622","label":"Blurred vision","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001289","label":"Confusion","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000651","label":"Diplopia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030826","label":"Eyelid fasciculation","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012378","label":"Fatigue","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002315","label":"Headache","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002076","label":"Migraine","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002018","label":"Nausea","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002013","label":"Vomiting","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0007670","label":"Abnormal vestibulo-ocular reflex","frequency":"Excluded (0%)","criteria":null},{"hpo":"HP:0410263","label":"Brain imaging abnormality","frequency":"Excluded (0%)","criteria":null}]}}