Phacoanaphylactic uveitis
Synonyms: Endophthalmitis phacoanaphylactica · Lens-induced endophthalmitis · Lens-induced iridocyclitis · Lens-induced uveitis · Phacoallergic endophthalmitis · Phacoantigenic endophthalmitis · Phako-anaphylactic endophthalmitis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adult
- Status
- active
A rare ophthalmic disorder characterized by a zonal granulomatous inflammatory reaction centered around the lens secondary to its traumatic rupture. Signs and symptoms include photophobia, ocular irritation or pain, blurred vision, redness, mutton-fat keratic precipitates, posterior synechiae, and sometimes hypopyon. Intraocular pressure may be elevated due to blockage of the trabecular meshwork by inflammatory cells or lens material.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Phacoanaphylactic uveitis | Endophthalmitis phacoanaphylactica · Lens-induced endophthalmitis · Lens-induced iridocyclitis · Lens-induced uveitis · Phacoallergic endophthalmitis · Phacoantigenic endophthalmitis · Phako-anaphylactic endophthalmitis |
| fr | Uvéite phacoanaphylactique | Endophtalmie phacoanaphylactique · Phacoanaphylaxie · Uvéite phacoantigénique |
| de | Uveitis, phakoanaphylaktische | Endophthalmitis phacoanaphylactica · Linsen-abhängige Endophthalmitis · Linsen-induzierte Iridozyklitis · Linsen-induzierte Uveitis · Phakoallergische Endophthalmitis · Phakoanaphylaktische Endophthalmitis |
| es | Uveítis facoanafiláctica | Endoftalmitis facoalérgica · Endoftalmitis facoanafiláctica · Endoftalmitis facoantigénica · Endoftalmitis inducida por lentes · Iridociclitis inducida por lentes · Uveítis inducida por lentes |
| it | Uveite facoanafilattica | Endoftalmite cristallino-indotta · Endoftalmite faco-anafilattica · Endoftalmite facoallergica · Endoftalmite facoanafilattica · Endoftalmite facoantigenica · Glaucoma facolitico · Iridociclite cristallino-indotta · Uveite cristallino-indotta |
| nl | Faco-anafylactische uveïtis | Endophthalmitis phacoanaphylactica · Faco-allergische endoftalmitis · Faco-anafylactische endoftalmitis · Faco-antigene endoftalmitis · Lens-geïnduceerde endoftalmitis · Lens-geïnduceerde iridocyclitis · Lens-geïnduceerde uveïtis |
| pt | Uveíte facoanafilática | |
| pl | Fakoanafilaktyczne zapalenie błony naczyniowej | Jaskra fakolityczna · Zapalenie błony naczyniowej pochodzenia soczewkowego · Zapalenie błony wewnętrzej fotoanafilaktyczne · Zapalenie błony wewnętrznej wywołane soczewkami · Zapalenie fotoalergiczne · Zapalenie tęczówki i ciała rzęskowego wywołane soczewkami |
| cs | Fakoanafylaktická uveitida | Fakoanafylaktická endoftalmitida · Fakoalergická endoftalmitida · Fakoantigenní endoftalmitida · Endoftalmitida vyvolaná čočkou · Iridocyklitida vyvolaná čočkou · Uveitida vyvolaná čočkou |
| uk | Факоанафілактичний увеїт | Ендофтальміт факоанафілактичний · Ендофтальміт, спричинений лінзами · Іридоцикліт, спричинений лінзами · Увеїт, спричинений лінзами · Факоалергічний ендофтальміт · Факоантигенний ендофтальміт · Фако-анафілактичний ендофтальміт |
| zh | 晶状体过敏性葡萄膜炎 | 晶状体成分过敏性眼内炎 |
| tr | Fakoanafilaktik üveit | Lens kaynaklı üveit · Lens kaynaklı iridosiklit · Lens kaynaklı endoftalmi · Fakoalerjik endoftalmi · Fakoantijenik endoftalmi · Endoftalmi fakoanafilaktika · Phako-anafilaktik endoftalmi |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | H20.2 | E | specific | validated |
| ICD-11 | 9A96.Y | NTBT | index | validated |
| MONDO | 0016207 | E | validated | |
| UMLS | C1444621 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:306648Non-infectious anterior uveitis
rare ophthalmic disorders
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
30 annotations · validated 2021-12-08| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0200026 | Ocular pain | |
| HP:0500081 | Pseudophakia | |
| HP:0000572 | Visual loss | |
| Frequent (79-30%) | ||
| HP:0011488 | Abnormal corneal endothelium morphology | |
| HP:0000615 | Abnormal pupil morphology | |
| HP:0012122 | Anterior uveitis | |
| HP:0000622 | Blurred vision | |
| HP:0030953 | Conjunctival hyperemia | |
| HP:0000491 | Keratitis | |
| HP:0000613 | Photophobia | |
| HP:0012123 | Posterior uveitis | |
| HP:0025337 | Red eye | |
| HP:0007773 | Vitreoretinopathy | |
| Occasional (29-5%) | ||
| HP:0030485 | Abnormal amplitude of pattern electroretinogram | |
| HP:0030486 | Abnormal timing of pattern electroretinogram | |
| HP:0004327 | Abnormal vitreous humor morphology | |
| HP:0025561 | Anterior chamber cells grade 1+ | |
| HP:0031618 | Anterior chamber flare grade 1+ | |
| HP:0025341 | Corneal keratic precipitates | |
| HP:0012040 | Corneal stromal edema | |
| HP:0011505 | Cystoid macular edema | |
| HP:0011886 | Hyphema | |
| HP:0031615 | Hypopyon | |
| HP:0040049 | Macular edema | |
| HP:0007906 | Ocular hypertension | |
| HP:0012121 | Panuveitis | |
| HP:0011484 | Posterior synechiae of the anterior chamber | |
| HP:0008030 | Retinal arteritis | |
| HP:0007917 | Tractional retinal detachment | |
| HP:0011531 | Vitritis | |
Run the differential on the 3 obligate / very frequent terms
Annotation source: 32999673[PMID]_32808145[PMID]_31907641[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/209959
- This record as JSON: /data/d/209959.json