ORPHA:2014
Cleft palate
- Type
- Clinical group
- Group
- Group of disorders
- Inheritance
- Multigenic/multifactorial, Not applicable
- Age of onset
- Antenatal, Neonatal
- Status
- active
A fissure type embryopathy that affects the soft and hard palate to varying degrees.
1
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Cleft palate | |
| fr | Fente du palais | Fente palatine |
| de | Gaumenspalte | |
| es | Paladar hendido | |
| it | Palatoschisi | |
| nl | Gespleten verhemelte | |
| pt | Fenda palatina | |
| pl | Rozszczep podniebienia | |
| cs | Rozštěp patra | |
| uk | Розщеплення піднебіння | |
| zh | 腭裂 | |
| tr | Yarık dudak |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| OMIM | 119540 | E | validated | |
| ICD-10 | Q35 | E | specific | validated |
| ICD-11 | LA42 | E | specific | validated |
| MONDO | 0016064 | E | validated | |
| MONDO | 16064 | E | validated | |
| MeSH | D002972 | E | validated | |
| UMLS | C0008925 | E | validated | |
| GARD | 1896 | E | validated | |
| MedDRA | 10009269 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
3
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:155832Rare head and neck malformation
rare developmental anomalies during embryogenesis - ORPHA:68329Rare maxillo-facial surgical disease
rare surgical maxillo-facial diseases
4
Genes
0 directOrphanet records no gene directly on this code.
5
Prevalence and incidence
54 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Prevalence at birth | 1-5 / 10 000 | 53.6 / 100 000 | Europe | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Europe | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 19.6 / 100 000 | Austria | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2009[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Austria | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2009[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 40.8 / 100 000 | Belgium | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Belgium | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 56.8 / 100 000 | Croatia | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Croatia | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Prevalence at birth | >1 / 1000 | 127.6 / 100 000 | Denmark | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Point prevalence | >1 / 1000 | — | Denmark | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 25.5 / 100 000 | France | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | France | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 47.5 / 100 000 | Germany | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Germany | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Prevalence at birth | 6-9 / 10 000 | 67.5 / 100 000 | Hungary | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Point prevalence | 6-9 / 10 000 | — | Hungary | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 54.2 / 100 000 | Ireland | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Ireland | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 39.6 / 100 000 | Italy | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Italy | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Prevalence at birth | 6-9 / 10 000 | 74.7 / 100 000 | Malta | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Point prevalence | 6-9 / 10 000 | — | Malta | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 11.7 / 100 000 | Netherlands | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Netherlands | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Prevalence at birth | 6-9 / 10 000 | 65.4 / 100 000 | Norway | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Point prevalence | 6-9 / 10 000 | — | Norway | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 36.5 / 100 000 | Poland | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Poland | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 14.2 / 100 000 | Portugal | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Portugal | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 30.7 / 100 000 | Spain | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Spain | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2010[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 25.1 / 100 000 | Switzerland | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Switzerland | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Prevalence at birth | 6-9 / 10 000 | 60.2 / 100 000 | United Kingdom | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Point prevalence | 6-9 / 10 000 | — | United Kingdom | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Prevalence at birth | 1-5 / 10 000 | 57.2 / 100 000 | Ukraine | Value and class | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Point prevalence | 1-5 / 10 000 | — | Ukraine | Class only | Validated | EUROCAT European surveillance of congenital anomalies 2011[OTHER] |
| Prevalence at birth | >1 / 1000 | 101.2 / 100 000 | Australia | Value and class | Validated | 23371924[PMID] |
| Point prevalence | >1 / 1000 | — | Australia | Class only | Not yet validated | 23371924[PMID] |
| Prevalence at birth | 1-5 / 10 000 | 52 / 100 000 | Chile | Value and class | Validated | 11372296[PMID] |
| Point prevalence | 1-5 / 10 000 | — | Chile | Class only | Not yet validated | 11372296[PMID] |
| Prevalence at birth | 1-5 / 10 000 | 27 / 100 000 | Sudan | Value and class | Validated | 15854114[PMID] |
| Point prevalence | 1-5 / 10 000 | — | Sudan | Class only | Not yet validated | 15854114[PMID] |
| Prevalence at birth | 1-5 / 10 000 | 26 / 100 000 | Iran, Islamic Republic of | Value and class | Validated | 20648890[PMID] |
| Point prevalence | 1-5 / 10 000 | — | Iran, Islamic Republic of | Class only | Not yet validated | 20648890[PMID] |
| Prevalence at birth | 1-5 / 10 000 | 27 / 100 000 | Mexico | Value and class | Validated | 8442867[PMID] |
| Point prevalence | 1-5 / 10 000 | — | Mexico | Class only | Not yet validated | 8442867[PMID] |
| Prevalence at birth | 1-9 / 100 000 | 4 / 100 000 | Bolivia | Value and class | Validated | 14989684[PMID] |
| Point prevalence | 1-9 / 100 000 | — | Bolivia | Class only | Not yet validated | 14989684[PMID] |
| Prevalence at birth | 6-9 / 10 000 | 68 / 100 000 | Specific population | Value and class | Validated | 15516165[PMID] |
| Point prevalence | 6-9 / 10 000 | — | Specific population | Class only | Validated | 15516165[PMID] |
| Prevalence at birth | 1-5 / 10 000 | 40 / 100 000 | Taiwan, Province of China | Value and class | Validated | 23555592[PMID] |
| Point prevalence | 1-5 / 10 000 | — | Taiwan, Province of China | Class only | Not yet validated | 23555592[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
6
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
7
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/2014
- This record as JSON: /data/d/2014.json