Chromomycosis
Synonyms: Chromoblastomycosis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
Chromomycosis is a chronic cutaneous and subcutaneous fungal infection, found mainly in subtropical and tropical areas (in soil and plant debris and transmitted by traumatic inoculation), and characterized clinically by slow growing, verrucous nodules, squamous plaques, or chronic limited lesions which are most commonly found on the lower limbs and which are characterized histologically by the presence of muriform cells. It is caused by dematiaceous fungi, with the main etiological agents being <i>Fonsecaea pedrosoi</i>, <i>Phialophora verrucosa</i> and <i>Cladophialophora carrionii</i>. Rarely, it can be caused by <i>Rhinocladiella aquaspersa</i>.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Chromomycosis | Chromoblastomycosis |
| fr | Chromomycose | Chromoblastomycose |
| de | Chromomykose | Chromoblastomykose |
| es | Cromomicosis | Cromoblastomicosis |
| it | Cromomicosi | Cromoblastomicosi |
| nl | Chromomycosis | = en |
| pt | Cromomicose | |
| pl | Chromomikoza | = en |
| cs | Chromomykóza | Chromoblastomykóza |
| uk | Хромомікоз | Хромобластомікоз |
| zh | 色素性真菌病 | 着色真菌病 |
| tr | Kromomikoz | Kromoblastomikoz |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | B43.0 | BTNT | specific | validated |
| ICD-10 | B43.1 | BTNT | specific | validated |
| ICD-10 | B43.2 | BTNT | specific | validated |
| ICD-10 | B43.8 | BTNT | specific | validated |
| ICD-10 | B43.9 | BTNT | specific | validated |
| ICD-11 | 1F24 | E | specific | validated |
| MONDO | 0015908 | E | validated | |
| MeSH | D002862 | E | validated | |
| UMLS | C0008582 | E | validated | |
| GARD | 1319 | E | validated | |
| MedDRA | 10008803 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163591Rare mycosis
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
33 annotations · validated 2020-04-15| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0002814 | Abnormality of the lower limb | |
| HP:0000989 | Pruritus | |
| Frequent (79-30%) | ||
| HP:0001760 | Abnormal foot morphology | |
| HP:0025528 | Annular cutaneous lesion | |
| HP:0000969 | Edema | |
| HP:0025475 | Erythematous macule | |
| HP:0025474 | Erythematous plaque | |
| HP:0000962 | Hyperkeratosis | |
| HP:0045059 | Hyperkeratotic papule | |
| HP:0040009 | Hyperparakeratosis | |
| HP:0001004 | Lymphedema | |
| HP:0003550 | Predominantly lower limb lymphedema | |
| HP:0025527 | Serpiginous cutaneous lesion | |
| HP:0001482 | Subcutaneous nodule | |
| HP:0012500 | Verrucous papule | |
| Occasional (29-5%) | ||
| HP:0002817 | Abnormality of the upper limb | |
| HP:0000987 | Atypical scarring of skin | |
| HP:0001053 | Hypopigmented skin patches | |
| HP:0031842 | Lymphangiectasis | |
| HP:0002718 | Recurrent bacterial infections | |
| HP:0011276 | Vascular skin abnormality | |
| Very rare (<4-1%) | ||
| HP:0002088 | Abnormal lung morphology | |
| HP:0000163 | Abnormal oral cavity morphology | |
| HP:0031013 | Ankylosis | |
| HP:0000656 | Ectropion | |
| HP:0500043 | Eyelid retraction | |
| HP:0011334 | Facial shape deformation | |
| HP:0002721 | Immunodeficiency | |
| HP:0000491 | Keratitis | |
| HP:0001097 | Keratoconjunctivitis sicca | |
| HP:0007606 | Multiple cutaneous malignancies | |
| HP:0002797 | Osteolysis | |
| HP:0002860 | Squamous cell carcinoma | |
Run the differential on the 2 obligate / very frequent terms
Annotation source: 27856522[PMID]_30066754[PMID]_30113072[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/182
- This record as JSON: /data/d/182.json