Adult intestinal botulism
Synonyms: Adult intestinal colonization botulism · Adult intestinal toxemia botulism · Adult intestinal toxin-mediated botulism · Infant-like botulism
- Type
- Clinical subtype
- Group
- Subtype of disorder
- Age of onset
- Adult
- Status
- active
A very rare form of botulism, a rare acquired neuromuscular junction disease with descending flaccid paralysis caused by botulinum neurotoxins (BoNTs), and is due to intestinal colonization by <i>Clostridium botulinum</i> leading to toxin-mediated infection with toxemia.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Adult intestinal botulism | Adult intestinal colonization botulism · Adult intestinal toxemia botulism · Adult intestinal toxin-mediated botulism · Infant-like botulism |
| fr | Botulisme intestinal de l'adulte | Botulisme "infant-like" de l'adulte · Botulisme colonisant · Botulisme par colonisation intestinale de l'adulte · Botulisme par toxi-infection intestinale de l'adulte |
| de | Botulismus, intestinaler, adulter | Botulismus, intestinaler, des Erwachsenen · Erwachsenenbotulismus |
| es | Botulismo intestinal del adulto | Botulismo por colonización intestinal en el adulto · Botulismo similar al infantil · Botulismo con toxemia intestinal de adultos · Botulismo intestinal del adulto por toxinas |
| it | Botulismo intestinale dell'adulto | Botulismo dell'adulto da colonizzazione intestinale · Botulismo dell'adulto da tossiemia intestinale · Botulismo infantile-simile · Botulismo intestinale tossino-mediato dell'adulto |
| nl | Intestinaal botulisme bij volwassene | Infantiel gelijkend botulisme · Intestinaal kolonisatiebotulisme bij volwassene · Intestinaal toxemisch botulisme bij volwassene · Intestinaal toxinegemedieerd botulisme bij volwassene |
| pt | Botulismo intestinal do adulto | |
| pl | Botulizm jelitowy dorosłych | = en |
| cs | Adultní střevní botulismus | Adultní střevní kolonizující botulismus · Adultní střevní toxemický botulismus · Adultní střevní botulismus způsobený toxinem · Botulismus podobný dětskému |
| uk | Кишковий ботулізм у дорослих | Ботулізм кишкової колонізації у дорослих · Ботулізм з кишковою токсикоінфекцією у дорослих · Ботулізм, спричинений кишковим токсином у дорослих · Дитячий ботулізм |
| zh | 成年型肠肉毒中毒 | 成人型肠毒素介导肉毒中毒 |
| tr | Yetişkin bağırsak botulizmi | Bebek-benzeri botulizm · Erişkin bağırsak toksemi botulizmi · Erişkin bağırsak kolonizasyonu botulizmi · Erişkin bağırsak toksin aracılı botulizm |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A05.1 | NTBT | attributed | validated |
| ICD-11 | 1A11.1 | NTBT | index | validated |
| MONDO | 0015806 | E | validated | |
| UMLS | C4289991 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:178481Intestinal botulism
rare neurological diseases; rare ophthalmic disorders; rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Cases/families | 19 cases | Worldwide | Case(s) | Validated | [EXPERT] | |
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
9 annotations · validated 2016-06-01| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0100021 | Cerebral palsy | |
| HP:0006824 | Cranial nerve paralysis | |
| HP:0006597 | Diaphragmatic paralysis | |
| HP:0000651 | Diplopia | |
| HP:0001324 | Muscle weakness | |
| HP:0000508 | Ptosis | |
| Frequent (79-30%) | ||
| HP:0002014 | Diarrhea | |
| HP:0002094 | Dyspnea | |
| HP:0002747 | Respiratory insufficiency due to muscle weakness | |
Run the differential on the 6 obligate / very frequent terms
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/178487
- This record as JSON: /data/d/178487.json