Diphtheria
- Type
- Disease
- Group
- Disorder
- Age of onset
- All ages
- Status
- active
A rare bacterial infectious disease characterized by an affliction of the upper respiratory tract mediated by the toxin of <i>Corynebacterium diphtheriae</i>. Symptoms include formation of an inflammatory pseudomembrane, fever, sore throat, headaches, coughing, dysphagia, dyspnea, and prominently swollen cervical lymph nodes. The disease may lead to respiratory failure and severe toxin-mediated damage of internal organs, including the heart and kidneys. A cutaneous form of diphtheria is more common in tropical climates and usually follows an indolent course.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Diphtheria | |
| fr | Diphtérie | |
| de | Diphterie | |
| es | Difteria | |
| it | Difterite | |
| nl | Difterie | |
| pt | Difteria | |
| pl | Błonica | |
| cs | Záškrt | Diftérie · Mázdřivka |
| uk | Дифтерія | |
| zh | 白喉 | |
| tr | Difteri |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A36.0 | BTNT | specific | validated |
| ICD-10 | A36.1 | BTNT | specific | validated |
| ICD-10 | A36.2 | BTNT | specific | validated |
| ICD-10 | A36.3 | BTNT | specific | validated |
| ICD-10 | A36.8 | BTNT | specific | validated |
| ICD-10 | A36.9 | BTNT | specific | validated |
| ICD-11 | 1C17 | E | specific | validated |
| ICD-11 | 1C17.0 | BTNT | specific | validated |
| ICD-11 | 1C17.1 | BTNT | specific | validated |
| ICD-11 | 1C17.2 | BTNT | specific | validated |
| ICD-11 | 1C17.3 | BTNT | specific | validated |
| ICD-11 | 1C17.Y | BTNT | attributed | validated |
| MONDO | 0005504 | E | validated | |
| MeSH | D004165 | E | validated | |
| UMLS | C0012546 | E | validated | |
| GARD | 1875 | E | validated | |
| MedDRA | 10013023 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163582Rare bacterial infectious disease
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | <1 / 1 000 000 | — | Europe | Class only | Validated | European Centre for Disease prevention and Control 2011[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/1679
- This record as JSON: /data/d/1679.json