ORPHA:139417
Acute transverse myelitis
- Type
- Disease
- Group
- Disorder
- Age of onset
- Adolescent, Adult, Childhood, Elderly, Infancy
- Status
- active
A rare inflammatory demyelinating disorder of the spinal cord that can be either idiopathic (IATM) or secondary to a known cause (SATM).
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Acute transverse myelitis | |
| fr | Myélite transverse aiguë | |
| de | Myelitis, akute transverse | Querschnittsmyelitis |
| es | Mielitis transversa aguda | |
| it | Mielite trasversa acuta | |
| nl | Acute transversale myelitis | Acute myelitis transversa |
| pt | Mielite transversa, aguda | |
| pl | Ostre poprzeczne zapalenie rdzenia | |
| cs | Akutní transverzální myelitida | |
| uk | Гострий поперечний мієліт | |
| zh | 急性横贯性脊髓炎 | |
| tr | Akut transvers miyelit |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G37.3 | NTBT | attributed | validated |
| ICD-11 | 8A41.0 | NTBT | index | validated |
| MONDO | 0015342 | E | validated | |
| UMLS | C0270627 | E | validated | |
| GARD | 19913 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:102000Medullar disease
rare neurological diseases - ORPHA:182064Rare neuroinflammatory or neuroimmunological disease
rare neurological diseases
Codes that Orphanet moved or referred to this one:
- ORPHA:139420OBSOLETE: Secondary acute transverse myelitis referred to · inactive
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
3 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | 1-9 / 100 000 | 8.6 / 100 000 | United States | Value and class | Validated | 31235660[PMID] |
| Point prevalence | 1-9 / 100 000 | 7.9 / 100 000 | United States | Value and class | Validated | 31235660[PMID] |
| Annual incidence | 1-9 / 100 000 | 4.72 / 100 000 | Worldwide | Value and class | Validated | 19812117[PMID]_19896453[PMID]_31235660[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
53 annotations · validated 2021-11-18| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Frequent (79-30%) | ||
| HP:0012332 | Abnormal autonomic nervous system physiology | |
| HP:0002071 | Abnormality of extrapyramidal motor function | |
| HP:5000013 | Anti-GFAP antibody | |
| HP:0012229 | CSF pleocytosis | |
| HP:0002922 | Increased CSF protein concentration | |
| HP:0001324 | Muscle weakness | |
| HP:0003474 | Somatic sensory dysfunction | |
| Occasional (29-5%) | ||
| HP:0031845 | Abnormal libido | |
| HP:0004370 | Abnormality of temperature regulation | |
| HP:0025615 | Abscess | |
| HP:0032492 | Anti-myelin oligodendrocyte glycoprotein antibody positivity | |
| HP:0002960 | Autoimmunity | |
| HP:0005341 | Autonomic bladder dysfunction | |
| HP:0003487 | Babinski sign | |
| HP:0003418 | Back pain | |
| HP:0007305 | CNS demyelination | |
| HP:0002019 | Constipation | |
| HP:0011967 | Decreased circulating copper concentration | |
| HP:0100502 | Decreased circulating vitamin B12 concentration | |
| HP:0032283 | Disseminated nontuberculous mycobacterial infection | |
| HP:0010835 | Dissociated sensory loss | |
| HP:0009053 | Distal lower limb muscle weakness | |
| HP:0012534 | Dysesthesia | |
| HP:0032271 | Extrapulmonary tuberculosis | |
| HP:0012378 | Fatigue | |
| HP:0001945 | Fever | |
| HP:0001288 | Gait disturbance | |
| HP:0002578 | Gastroparesis | |
| HP:0001347 | Hyperreflexia | |
| HP:0000822 | Hypertension | |
| HP:0011972 | Hypoglycorrhachia | |
| HP:0002721 | Immunodeficiency | |
| HP:0010831 | Impaired proprioception | |
| HP:0002495 | Impaired vibratory sensation | |
| HP:0031700 | Invasive parasitic infection | |
| HP:0001287 | Meningitis | |
| HP:0010547 | Muscle flaccidity | |
| HP:0031179 | Nuchal rigidity | |
| HP:0001278 | Orthostatic hypotension | |
| HP:0002590 | Paralytic ileus | |
| HP:0002385 | Paraparesis | |
| HP:0010550 | Paraplegia | |
| HP:0003401 | Paresthesia | |
| HP:0031691 | Severe viral infection | |
| HP:0001257 | Spasticity | |
| HP:0002138 | Subarachnoid hemorrhage | |
| HP:0002725 | Systemic lupus erythematosus | |
| HP:0003484 | Upper limb muscle weakness | |
| HP:0002493 | Upper motor neuron dysfunction | |
| HP:0002839 | Urinary bladder sphincter dysfunction | |
| HP:0000020 | Urinary incontinence | |
| HP:0000016 | Urinary retention | |
| Very rare (<4-1%) | ||
| HP:0200023 | Priapism | |
Annotation source: 29375121[PMID]_23186897[PMID]_24099672[PMID]
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/139417
- This record as JSON: /data/d/139417.json