ORPHA:137686
Asherman syndrome
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adult
- Status
- active
A rare, acquired uterine disease characterized by intrauterine adhesions associated with a history of curettage or intrauterine surgery and gynecological symptoms (secondary amenorrhea, hypomenorrhea, pelvic pain, infertility or pregnancy loss).
1
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Asherman syndrome | |
| fr | Syndrome d'Asherman | |
| de | Asherman-Syndrom | |
| es | Síndrome de Asherman | |
| it | Sindrome di Asherman | Adesioni intrauterine · Sinechie intrauterine |
| nl | Syndroom van Asherman | Intra-uteriene adhesies · Intra-uteriene synechiae |
| pt | Síndrome de Asherman | |
| pl | Zespół Ashermana | Zrosty wewnątrzmaciczne |
| cs | Ashermanův syndrom | Intrauterinní adheze · Děložní synechie |
| uk | Синдром Ашермана | |
| zh | Asherman 综合征 | |
| tr | Asherman sendromu |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | N85.6 | E | specific | validated |
| ICD-11 | GA16.2 | E | specific | validated |
| MONDO | 0015299 | E | validated | |
| UMLS | C0156372 | E | validated | |
| GARD | 5853 | E | validated | |
| MedDRA | 10053868 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
3
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:180205Rare non-malformative uterovaginal or vulvovaginal disease
rare gynecological and obstetric diseases
No children.
4
Genes
0 directOrphanet records no gene directly on this code.
5
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 44 / 100 000 | Europe | Value and class | Validated | European Medicines Agency 2017[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
6
HPO phenotypes
11 annotations · validated 2019-06-25| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Frequent (79-30%) | ||
| HP:0000140 | Abnormality of the menstrual cycle | |
| HP:0000868 | Decreased fertility in females | |
| HP:0000876 | Oligomenorrhea | |
| Occasional (29-5%) | ||
| HP:0100607 | Dysmenorrhea | |
| HP:0002574 | Episodic abdominal pain | |
| HP:0000789 | Infertility | |
| HP:0100608 | Metrorrhagia | |
| HP:0000869 | Secondary amenorrhea | |
| HP:0005268 | Spontaneous abortion | |
| Very rare (<4-1%) | ||
| HP:0100767 | Abnormality of the placenta | |
| HP:0031035 | Chronic infection | |
Annotation source: 28846336[PMID]_29493709[PMID]_30713131[PMID]_30936754[PMID]
7
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/137686
- This record as JSON: /data/d/137686.json