{"orpha":99932,"name":"Heiner syndrome","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Cow's milk-induced pulmonary hypersensitivity syndrome"],"definition":"Heiner syndrome, also called cow's milk hypersensitivity, is a food induced pulmonary hypersensiting syndrome that affects primarily infants and that is characterized by pulmonary hemosiderosis, digestive bleeding, anemia and poor growing, improving with elimination of cow's milk from the diet.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-99932/","orphanet_url":"https://www.orpha.net/en/disease/detail/99932","names":{"fr":{"name":"Syndrome de Heiner","synonyms":["Syndrome d'hypersensibilité pulmonaire induit par le lait de vache"],"definition":"Le syndrome de Heiner, aussi nommé hypersensibilité au lait de vache, est un syndrome d'hypersensibilité pulmonaire induite par la nourriture, affectant en premier lieu les nourrissons, et caractérisé par une hémosidérose pulmonaire , des hémorragies digestives et un retard de croissance, s'améliorant avec l'élimination du lait de vache du régime alimentaire."},"de":{"name":"Heiner-Syndrom","synonyms":["Kuhmilch-Hypersensitivität","Kuhmilch-induziertes pulmonales Hypersensitivitätssyndrom"],"definition":"Das Heiner-Syndrom, auch Kuhmilchallergie genannt, ist ein nahrungsmittelbedingtes pulmonales Hypersensitivitätssyndrom, von dem besonders Kleinkinder betroffen sind. Die Krankheit ist gekennzeichnet durch Lungen-Hämosiderose (s. dort), Blutungen im Verdauungstrakt, Anämie und mangelhaftes Wachstum. Durch Vermeidung von Milch werden die Symptome gebessert."},"es":{"name":"Síndrome de Heiner","synonyms":["Síndrome de hipersensibilidad pulmonar inducido por la leche de vaca"],"definition":"El síndrome de Heiner, también llamado hipersensibilidad a la leche de vaca, es un síndrome de hipersensibilidad pulmonar inducido por la comida que afecta principalmente a niños y que se caracteriza por una hemosiderosis pulmonar (consulte este término), sangrados digestivos, anemia y crecimiento pobre, que mejora con la eliminación de la leche."},"it":{"name":"Sindrome di Heiner","definition":"La sindrome di Heiner, nota anche come ipersensibilità al latte vaccino, è una sindrome da ipersensibilità polmonare indotta dagli alimenti, che interessa primariamente i neonati, con emosiderosi polmonare (si veda questo termine), emorragia intestinale, anemia, scarsa crescita. Il quadro migliora con l'eliminazione del latte dalla dieta."},"nl":{"name":"Syndroom van Heiner","synonyms":["Door koemelk geïnduceerd pulmonale overgevoeligheidssyndroom"],"definition":"Een door voedsel geïnduceerd syndroom van pulmonale hypersensitiviteit dat vooral zuigelingen treft, en gekenmerkt wordt door pulmonale hemosiderose, bloeding van spijsverteringsstelsel, anemie, en ondermaatse groei. Verbetering treedt op wanneer koemelk wordt geweerd uit het dieet."},"pt":{"name":"Síndrome Heiner","synonyms":["Síndrome de hipersensibilidade pulmonar induzido pelo leite de vaca"]},"pl":{"name":"Zespół Heinera","synonyms":["Nadwrażliwość na krowie mleko"]},"cs":{"name":"Heinerův syndrom","synonyms":["Přecitlivělost na kravské mléko"]},"uk":{"name":"Синдром Гейнера","synonyms":["Підвищена чутливість до коровячого молока"],"definition":"Heiner syndrome, also called cow's milk hypersensitivity, is a food induced pulmonary hypersensiting syndrome that affects primarily infants and that is characterized by pulmonary hemosiderosis (see this term), digestive bleeding, anemia and poor growing, improving with elimination of cow's milk from the diet."},"zh":{"name":"Heiner综合征","synonyms":["牛乳过敏症"],"definition":"海纳综合征，又称牛乳过敏，是一种主要影响婴儿的食物引起的肺感觉过敏综合征，其特征是肺含铁血黄素沉着症(见该词条)、消化道出血、贫血和生长不良，随着饮食中牛奶的减少而改善。"},"tr":{"name":"Heiner sendromu","synonyms":["İnek sütüne aşırı duyarlılık"]}},"xrefs":[{"source":"ICD-10","code":"E83.1+","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-10","code":"J99.8*","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"CB05.5","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"187112249"},{"source":"MONDO","code":"0020554","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C3873343","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97955,"name":"Rare respiratory disease"},"parents":[{"orpha":264944,"name":"Secondary interstitial lung disease in childhood and adulthood","classifications":[184,233]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Infancy"],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.07,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}