{"orpha":99903,"name":"Spirillary rat-bite fever","type":"Etiological subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":["Sodoku"],"definition":"A rare bacterial zoonosis characterized by inflammation which appears at the site of a rat bite or scratch that becomes painful, indurated, edematous and may ulcerate. The inflammation is followed by fever, vomiting and chills and is associated with local lymphadenopathy. Spirillary rat-bite fever (RBF), also known as Sodoku (Japanese for so: rat and doku: poison), is caused by the Gram-negative bacillus <i>Spirillum minus</i> and is transmitted to humans through the bites and scratches of rats.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-99903/","orphanet_url":"https://www.orpha.net/en/disease/detail/99903","names":{"fr":{"name":"Spirillose due aux morsures de rat","synonyms":["Sodoku"],"definition":"Zoonose bactérienne rare caractérisée par une inflammation apparaissant au niveau du site de la morsure ou de la griffure du rat, devenant douloureuse, indurée, oedémateuse et parfois ulcérée. L'inflammation associée à une lymphadénopathie locale, s'accompagne de fièvre, de vomissements et de frissons. La spirillose due aux morsures de rat, également connue sous le nom de Sodoku (so signifiant «&nbsp;rat&nbsp;» et doku «&nbsp;poison&nbsp;» en japonais), est causée par le bacille Gram négatif <i>Spirillum minus</i> et se transmet à l'Homme par les morsures et les griffures de rats."},"de":{"name":"Spirillen-Rattenbissfieber","synonyms":["Sodoku"],"definition":"Eine seltene bakterielle Zoonose, die durch eine Entzündung gekennzeichnet ist, die an der Stelle eines Rattenbisses oder -kratzers auftritt, schmerzhaft, verhärtet und ödematös ist und zu Geschwüren führen kann. Auf die Entzündung folgen Fieber, Erbrechen und Schüttelfrost, verbunden mit einer lokalen Lymphadenopathie. Das Spirilläre Rattenbissfieber (RBF), auch bekannt als Sodoku (japanisch für ,,so'': Ratte und ,,doku'': Gift), wird durch den gramnegativen Bazillus <i>Spirillum minus</i> verursacht und durch Bisse und Kratzer von Ratten auf den Menschen übertragen."},"es":{"name":"Fiebre espirilar por mordedura de rata","synonyms":["Sodoku"],"definition":"Es una zoonosis bacteriana poco frecuente caracterizada por inflamación que aparece en el sitio de una mordedura o arañazo de rata, que se vuelve doloroso, indurado, edematoso y puede ulcerarse. La inflamación se acompaña de fiebre, vómitos y escalofríos, y se asocia con linfadenopatía local. La fiebre espirilar por mordedura de rata (FMR), también conocida como sodoku (del japonés so: rata y doku: veneno), está causada por el bacilo gramnegativo <i>Spirillum minus</i> y se transmite a los humanos a través de mordeduras y arañazos de ratas."},"it":{"name":"Febbre spirillare da morso di ratto","synonyms":["Sodoku"]},"nl":{"name":"Spirillum-rattenbeetkoorts","synonyms":["Sodoku"],"definition":"Een zeldzame bacteriële zoönose, gekenmerkt door inflammatie die verschijnt ter hoogte van een beet of een krab van een rat, en die pijnlijk, hard en oedemateus wordt en kan verzweren. De inflammatie wordt gevolgd door koorts, braken en rillingen, en is geassocieerd met lokale lymfadenopathie. Spirillum-rattenbeetkoorts (RBF), ook gekend als Sodoku (van het Japanse so: rat, en doku: gif), wordt veroorzaakt door de gramnegatieve bacterie <i>Spirillum minus</i>, en wordt overgedragen op mensen door beten of krabben van ratten."},"pt":{"name":"Febre de mordedura da ratazana, espirilar","synonyms":["Sodoku"],"definition":"A febre de mordedura de rato espirilar, também conhecida como Sodoku (Japonês para rato e doku: veneno), é causada por bacilos Gram-negativos <i>Spirillum minus</i> e é transmitidia a humanos através de mordeduras e arranhadelas de ratazanas."},"pl":{"name":"Śrubowcowa gorączka szczurza","synonyms":["Sodoku"]},"cs":{"name":"Spirilární horečka z krysího kousnutí","synonyms":["Sodoku"]},"uk":{"name":"Спірилична лихоманка від укусу щура","synonyms":["Содоку"],"definition":"Spirillary rat-bite fever (RBF), also known as Sodoku (Japanese for so: rat and doku: poison), is caused by the Gram-negative bacillus <i>Spirillum minus</i> and is transmitted to humans through the bites and scratches of rats. The disease is mostly present in Asia."},"zh":{"name":"螺菌性鼠咬热","synonyms":["鼠咬热病"],"definition":"螺旋体咬伤热(RBF)，又称Sodoku(日语中SO：老鼠和doku：毒药)，由革兰氏阴性杆菌小螺菌 引起，通过老鼠的咬伤和抓伤传播给人类。这种疾病主要出现在亚洲。"},"tr":{"name":"Spiriler sıçan ısırığı ateşi","synonyms":["Sodoku"]}},"xrefs":[{"source":"ICD-10","code":"A25.0","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1B90.0","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1104357482"},{"source":"MONDO","code":"0020532","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0152062","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":31205,"name":"Rat-bite fever","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}