{"orpha":99868,"name":"Thymic carcinoma","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Thymic carcinoma (TC) is a type of thymic epithelial neoplasm characterized by a high malignant potential.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-99868/","orphanet_url":"https://www.orpha.net/en/disease/detail/99868","names":{"fr":{"name":"Carcinome thymique","definition":"Le carcinome thymique est un type de néoplasie épithéliale thymique caractérisé par un potentiel malin élevé."},"de":{"name":"Thymuskarzinom","synonyms":["Thymom, malignes"],"definition":"Das Thymuskarzinom (TC) ist eine Form der Thymusepithel-Neoplasmen (TEN) und gekennzeichnet durch ein hohes malignes Potential."},"es":{"name":"Carcinoma tímico","definition":"El carcinoma tímico es un tipo de neoplasia epitelial de timo (ver término) caracterizado por un alto potencial maligno"},"it":{"name":"Carcinoma del timo","synonyms":["Timoma maligno"]},"nl":{"name":"Thymuscarcinoom","synonyms":["Carcinoom van thymus"],"definition":"Thymuscarcinoom (TC) is een type epitheliaal neoplasma van de thymus (zie deze term), gekenmerkt door een hoog kwaadaardig potentieel."},"pt":{"name":"Carcinoma tímico","definition":"O carcinoma tímico (TC) é um tipo de neoplasia epitelial tímica (ver este termo), caracterizada por um elevado potencial maligno."},"pl":{"name":"Rak grasicy","synonyms":["Grasiczak złośliwy"]},"cs":{"name":"Karcinom thymu","synonyms":["Maligní thymom"]},"uk":{"name":"Карцинома тимусу","synonyms":["Злоякісна тимома"],"definition":"Thymic carcinoma (TC) is a type of thymic epithelial neoplasm (see this term) characterized by a high malignant potential."},"zh":{"name":"胸腺癌","synonyms":["恶性胸腺瘤"],"definition":"胸腺癌(TC)是一种胸腺上皮性肿瘤(见该词条)，其特点是恶性潜能高。"},"tr":{"name":"Timik karsinom","synonyms":["Habis timoma"]}},"xrefs":[{"source":"ICD-10","code":"C37","qualifier":"NTBT","icd_relation":"index","validated":true},{"source":"ICD-11","code":"2C27.0","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1351671383"},{"source":"MONDO","code":"0006451","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0205969","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10061031","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":3398,"name":"Thymic epithelial neoplasm","classifications":[202]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-06-01","source":null,"terms":[{"hpo":"HP:0100721","label":"Mediastinal lymphadenopathy","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0100521","label":"Neoplasm of the thymus","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0005345","label":"Abnormal vena cava morphology","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0100749","label":"Chest pain","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0012735","label":"Cough","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0006597","label":"Diaphragmatic paralysis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002094","label":"Dyspnea","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000969","label":"Edema","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0100540","label":"Palpebral edema","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0003473","label":"Fatigable weakness","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012378","label":"Fatigue","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000975","label":"Hyperhidrosis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001824","label":"Weight loss","frequency":"Occasional (29-5%)","criteria":null}]}}