{"orpha":99177,"name":"Isolated distichiasis","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Isolated distichiasis is a rare congenital eyelid anomaly characterized by an accessory row of eyelashes (that may be partial or complete) posterior to the normal row of cilia, at or close to the meibomian gland orifices, that is not associated with any other condition, and that may lead to ocular irritation and corneal damage if left untreated.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-99177/","orphanet_url":"https://www.orpha.net/en/disease/detail/99177","names":{"fr":{"name":"Distichiasis isolé","definition":"Le distichiasis isolé est une anomalie congénitale rare de la paupière caractérisée par la présence d'un rang de cils supplémentaire (qui peut être partiel ou complet) postérieurement au rang de cils normal, ou à proximité des orifices des glandes de Meibomius, sans aucune autre anomalie associée, et pouvant entraîner une irritation oculaire et une atteinte cornéenne en l'absence de traitement."},"de":{"name":"Distichiasis, isolierte","definition":"Die isolierte Distichiasis ist eine seltene angeborene Fehlbildung des Augenlids, die sich durch eine zusätzliche Wimpernreihe (partiell oder vollständig) auszeichnet. Sie liegt hinter den normalen Wimpern in unmittelbarer Nähe der Öffnungen der Meimbom-Talgdrüsen und ist mit keinen weiteren Auffälligkeiten assoziiert. Sie kann aber eine Augenreizung und Schäden an der Hornhaut verursachen, sollte sie unbehandelt bleiben."},"es":{"name":"Distiquiasis aislada","definition":"La distiquiasis aislada es una anomalía palpebral congénita rara caracterizada por una hilera supernumeraria de pestañas (que puede ser parcial o completa) posterior a la hilera de pestañas normal en las proximidades o sobre los orificios de las glándulas de Meibomio. No está asociada a ninguna otra condición y puede provocar irritación ocular y daño corneal si no se trata."},"it":{"name":"Distichiasi isolata","definition":"La distichiasi isolata è un'anomalia congenita rara della palpebra, caratterizzata da una doppia fila di ciglia (che può essere parziale o completa), posizionata posteriormente alla normale fila delle ciglia, sopra o vicino gli orifizi delle ghiandole meibomiane. Non si associa ad altre malattie; in assenza di trattamento, può provocare l'irritazione dell'occhio e il danno alla cornea."},"nl":{"name":"Geïsoleerde distichiase","definition":"Geïsoleerde distichiase is een zeldzame congenitale afwijking van het ooglid die wordt gekarakteriseerd door een extra rij wimpers (deels of volledig) achter de normale rij cilia, aan of nabij de uitgang van de klieren van Meibom. De ziekte is niet geassocieerd met een andere conditie en kan leiden tot irritatie van het oog en schade aan het hoornvlies indien een behandeling uitblijft."},"pt":{"name":"Distiquíase"},"pl":{"name":"Izolowana dwurzędowość rzęs"},"cs":{"name":"Izolovaná distichiáza"},"uk":{"name":"Ізольований дистихіоз","definition":"Isolated distichiasis is a rare congenital eyelid anomaly characterized by an accessory row of eyelashes (that may be partial or complete) posterior to the normal row of cilia, at or close to the meibomian gland orifices, that is not associated with any other condition, and that may lead to ocular irritation and corneal damage if left untreated."},"zh":{"name":"孤立型双睫症","definition":"孤立性双排睫毛是一种罕见的先天性眼睑畸形，以在正常睫毛后面或靠近睑板腺口处多出一排副睫毛(可能是部分的或完整的)为特征，与任何其他疾病无关，如果不治疗可能会引起眼部刺激和角膜损伤。"},"tr":{"name":"İzole distikiyaz"}},"xrefs":[{"source":"OMIM","code":"126300","qualifier":"E","icd_relation":null,"validated":true},{"source":"ICD-10","code":"Q10.3","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LA14.0Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"417920497"},{"source":"MONDO","code":"0007464","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5779555","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10066128","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":98594,"name":"Rare eyebrow/eyelash disorder","classifications":[147,156,189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}