{"orpha":99089,"name":"Abnormal number of coronary ostia","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare, congenital, non-syndromic heart malformation characterized by more or less than one coronary ostium at the left and at the right aortic sinus of Valsalva. It may be asymptomatic or it leads to myocardial ischemia and technical difficulties during coronary angiography.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-99089/","orphanet_url":"https://www.orpha.net/en/disease/detail/99089","names":{"fr":{"name":"Anomalie de nombre des ostia coronaires","definition":"Malformation cardiaque congénitale non syndromique rare caractérisée par plus d'un ou moins d'un ostium coronaire au niveau du sinus de Valsalva gauche et droit. La maladie peut être asymptomatique ou entraîner une ischémie myocardique et poser des difficultés techniques lors de l'angiographie coronaire."},"de":{"name":"Koronarostium, abnormale Anzahl"},"es":{"name":"Número anómalo de los ostia coronarios","definition":"Es una malformación cardíaca no sindrómica, congénita y poco frecuente, caracterizada por más o menos de un ostium coronario en los senos aórticos de Valsalva derecho e izquierdo. Puede ser asintomático o conducir a isquemia de miocardio y producir dificultades técnicas durante la angiografía coronaria."},"it":{"name":"Numero anomalo di osti coronarici","definition":"La presenza di un numero anomalo di osti coronarici è una cardiopatia congenita non sindromica, rara, caratterizzata da più o meno di un ostio coronarico a livello del seno aortico di Valsalva sinistro e destro. I pazienti possono essere asintomatici oppure presentare ischemia del miocardio e difficoltà tecniche nell'esecuzione dell'angiografia coronarica."},"nl":{"name":"Abnormaal aantal coronaire ostia","definition":"Een zeldzame, congenitale, niet-syndromale hartmalformatie, gekarakteriseerd door meer of minder dan één coronair ostium aan de linker en rechter sinus van Valsalva (sinus aortae). De aandoening kan asymptomatisch zijn, of kan leiden tot myocardiale ischemie en technische moeilijkheden tijdens coronaire angiografie."},"pt":{"name":"Óstio coronário, anomalia de número"},"pl":{"name":"Nieprawidłowa liczba ujść wieńcowych","definition":"*Nieprawidłowa liczba ujść wieńcowych jest rzadką, wrodzoną, izolowana wadą serca, która charakteryzuje się więcej niż jednym ujściem wieńcowym w lewej i prawej zatoce Valsalvy. Może przebiegać bezobjawowo lub być przyczyną niedokrwienia mięśnia sercowego oraz sprawiać trudności techniczne podczas koronarografii."},"cs":{"name":"Abnormální počet koronárních ostií"},"uk":{"name":"Аномальна кількість вусть коронарних артерій","definition":"A rare, congenital, non-syndromic heart malformation characterized by more or less than one coronary ostium at the left and at the right aortic sinus of Valsalva. It may be asymptomatic or it leads to myocardial ischemia and technical difficulties during coronary angiography."},"zh":{"name":"冠状窦口数目异常","definition":"该病是一种罕见的、先天性的、无综合征的心脏畸形，其特征是在 Valsalva左、右主动脉窦有一个或多个冠状静脉口。它可能是无症状的，也可能导致心肌缺血以及难以进行冠脉造影。"},"tr":{"name":"Anormal sayıda koroner osti"}},"xrefs":[{"source":"ICD-10","code":"Q24.5","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LA8C.Y","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0020425","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5191081","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":542822,"name":"Anomaly of the coronary ostia","classifications":[147,148]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}