{"orpha":99072,"name":"Congenital patent ductus arteriosus aneurysm","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare, congenital, arterial duct anomaly characterized by a saccular dilatation of the ductus arteriosus. It is often asymptomatic or presents shortly after birth with respiratory distress, stridor, cyanosis and/or weak cry. Complications, such as rupture, thromboembolism, infection, airway erosion and/or compression of the adjacent thoracic structures, can develop. Spontaneous resolution has been reported.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-99072/","orphanet_url":"https://www.orpha.net/en/disease/detail/99072","names":{"fr":{"name":"Anévrisme du canal artériel","definition":"Une anomalie rare et congénitale du canal artériel caractérisée par une dilatation sacculaire de ce canal. Elle est souvent asymptomatique ou se manifeste peu après la naissance par une détresse respiratoire, un stridor, une cyanose et/ou un faible cri. Des complications peuvent se développer, telles qu'une rupture, une thromboembolie, une infection, une érosion des voies aériennes et/ou une compression des structures thoraciques adjacentes. Une résolution spontanée a été rapportée."},"de":{"name":"Aneurysma des persistierenden Ductus arteriosus, kongenitales","definition":"Eine seltene, angeborene Anomalie des Ductus arteriosus, die durch eine sackförmige Erweiterung des Ductus arteriosus gekennzeichnet ist. Sie ist oft asymptomatisch oder präsentiert sich kurz nach der Geburt mit Atemnot, Stridor, Zyanose und/oder schwachem Schrei. Es kann zu Komplikationen wie Ruptur, Thromboembolie, Infektion, Erosion der Atemwege und/oder Kompression der angrenzenden thorakalen Strukturen kommen. Spontane Rückbildungen wurden beschrieben."},"es":{"name":"Aneurisma congénito del ductus arterioso persistente","definition":"Es una anomalía congénita poco frecuente del ductus arterial caracterizada por una dilatación sacular del ductus arterioso. A menudo es asintomático o se presenta poco después del nacimiento con dificultad respiratoria, estridor, cianosis y/o llanto débil. Se pueden desarrollar complicaciones tales como rotura, tromboembolismo, infección, erosión de las vías respiratorias y/o compresión de las estructuras torácicas adyacentes. Se ha reportado remisión espontánea."},"it":{"name":"Aneurisma congenito del dotto arterioso pervio","definition":"L'aneurisma congenito del dotto arterioso pervio è un difetto congenito raro del dotto arterioso, caratterizzato da dilatazione sacculare del dotto stesso. Spesso è asintomatico oppure esordisce subito dopo la nascita con distress respiratorio, stridore, cianosi e/o pianto debole. Possono insorgere complicanze come la rottura, il tromboembolismo, le infezioni, l'erosione delle vie aeree e/o la compressione delle strutture toraciche fiancheggianti. Sono stati segnalati casi di risoluzione spontanea."},"nl":{"name":"Congenitaal aneurysma van persisterende ductus arteriosus","definition":"Een zeldzame, congenitale anomalie van de ductus arteriosus, gekarakteriseerd door een sacculaire dilatatie van de ductus arteriosus. Het is vaak asymptomatisch of vertoont zich kort na de geboorte met ademnood, stridor, cyanose en/of zwak gehuil. Complicaties, zoals scheuring, trombo-embolie, infectie, erosie van luchtwegen en/of compressie van naburige thoracale structuren, kunnen ontwikkelen. Spontane resolutie werd reeds gerapporteerd."},"pt":{"name":"Aneurisma do canal arterial patente congénito"},"pl":{"name":"Wrodzony tętniak przetrwałego przewodu tętniczego"},"cs":{"name":"Vrozené aneuryzma ductus arteriosus pantens"},"uk":{"name":"Вроджена аневризма відкритої артеріальної протоки","definition":"A rare, congenital, arterial duct anomaly characterized by a saccular dilatation of the ductus arteriosus. It is often asymptomatic or presents shortly after birth with respiratory distress, stridor, cyanosis and/or weak cry. Complications, such as rupture, thromboembolism, infection, airway erosion and/or compression of the adjacent thoracic structures, can develop. Spontaneous resolution has been reported."},"zh":{"name":"先天性动脉导管未闭动脉瘤","definition":"该病是一种罕见的先天性动脉导管异常，特征是动脉导管呈囊状扩张。该病通常无症状或在出生后不久出现呼吸窘迫、喘鸣、紫绀和/或哭声微弱。并发症包括破裂、血栓栓塞、感染、气道侵蚀和/或邻近胸部结构受压。已有症状自发性消退的报告。"},"tr":{"name":"Doğumsal açık duktus arteriyozus anevrizması"}},"xrefs":[{"source":"ICD-10","code":"Q25.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LA8B.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1307324770"},{"source":"MONDO","code":"0020412","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4706391","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":95485,"name":"Arterial duct anomaly","classifications":[147,148,198]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}