{"orpha":99049,"name":"Pulmonary artery coming from patent ductus arteriosus","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Pulmonary artery coming from patent ductus arteriosus is a rare, congenital, non-syndromic heart malformation characterized by the presence of a single (or a double) patent ductus arteriosus which associates one or both pulmonary arteries originating from it. Manifestations are variable, frequently presenting with neonatal cyanosis, severe progressive hypoxia, persistent pulmonary hypertension, increased susceptibility to pulmonary infections, and thoracic asymmetry resulting from asymmetric lung volumes.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-99049/","orphanet_url":"https://www.orpha.net/en/disease/detail/99049","names":{"fr":{"name":"Artère pulmonaire naissant du canal artériel","definition":"Malformation cardiaque congénitale rare, non syndromique, caractérisée par la persistance du canal artériel simple (ou double) où prennent naissance une ou les deux artères pulmonaires. Variables, les manifestations les plus fréquentes sont une cyanose néonatale, une hypoxie progressive sévère, une hypertension pulmonaire persistante, une susceptibilité accrue aux infections pulmonaires et une asymétrie thoracique résultant d'une asymétrie des volumes pulmonaires."},"de":{"name":"Pulmonalarterie, dem offenem Ductus arteriosus entstammend"},"es":{"name":"Arteria pulmonar procedente de ductus arterioso persistente","definition":"Es una malformación cardíaca no sindrómica, congénita y poco frecuente, caracterizada por la presencia de un ductus arterioso persistente simple (o doble) del que se origina una o ambas arterias pulmonares. Las manifestaciones son variables, presentándose frecuentemente con cianosis neonatal, hipoxia progresiva severa, hipertensión pulmonar persistente, mayor susceptibilidad a las infecciones pulmonares y asimetría torácica resultante de la asimetría en los volúmenes pulmonares."},"it":{"name":"Arteria polmonare ad origine del dotto arterioso pervio","definition":"L'arteria polmonare ad origine dal dotto arterioso pervio è una cardiopatia congenita non sindromica rara, caratterizzata dalla presenza di un dotto arterioso pervio singolo (o doppio) da cui originano una/entrambe le arterie polmonari. I segni clinici sono variabili e spesso comprendono la cianosi neonatale, l'ipossia progressiva grave, l'ipertensione polmonare persistente, la maggiore suscettibilità alle infezioni polmonari e l'asimmetria del torace secondaria all'asimmetria dei volumi polmonari."},"nl":{"name":"Longslagader afkomstig van open ductus arteriosus","definition":"Longslagader afkomstig van open ductus arteriosus is een zeldzame, congenitale, niet-syndromale hartmalformatie die gekarakteriseerd wordt door de aanwezigheid van een enkele (of dubbele) persisterende ductus arteriosus waaruit één of beide longslagaders ontspringen. Manifestaties variëren en omvatten frequent neonatale cyanose, ernstige progressieve hypoxie, aanhoudende pulmonale hypertensie, verhoogde vatbaarheid voor longinfecties, en thoracale asymmetrie als gevolg van asymmetrische longvolumes."},"pt":{"name":"Artéria pulmonar proveniente de canal arterial patente"},"pl":{"name":"Tętnica płucna odchodząca od przetrwałego przewodu tętniczego"},"cs":{"name":"Plicnice vycházející z ductus arteriosus patens"},"uk":{"name":"Легенева артерія, яка відходить від відкритої артеріальної протоки","definition":"Pulmonary artery coming from patent ductus arteriosus is a rare, congenital, non-syndromic heart malformation characterized by the presence of a single (or a double) patent ductus arteriosus which associates one or both pulmonary arteries originating from it. Manifestations are variable, frequently presenting with neonatal cyanosis, severe progressive hypoxia, persistent pulmonary hypertension, increased susceptibility to pulmonary infections, and thoracic asymmetry resulting from asymmetric lung volumes."},"zh":{"name":"起自动脉导管未闭的肺动脉","definition":"该病是起源于动脉导管未闭的肺动脉是一种罕见的、先天性的、非综合征性的心脏畸形，其特征是存在一个(或两个)动脉导管未闭，它与起源于动脉导管的一条或两条肺动脉相连。临床表现多样，常表现为新生儿紫绀、严重进行性缺氧、持续性肺动脉高压、肺部感染易感性增加以及肺体积不对称引起的胸部不对称。"},"tr":{"name":"Patent duktus arteriyozustan gelen pulmoner arter"}},"xrefs":[{"source":"ICD-10","code":"Q25.7","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LA8B.1","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"16177108"},{"source":"MONDO","code":"0020390","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C3163916","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":1138,"name":"Abnormal origin of the pulmonary artery","classifications":[147,148]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}