{"orpha":98980,"name":"Cogan-Reese syndrome","type":"Clinical subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":[],"definition":"A clinical variant of iridocorneal endothelial (ICE) syndrome, characterized by variable iris atrophy, pigmented and pedunculated nodules on the iris and corneal abonormalities. Secondary glaucoma is also a common complication of the disease.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-98980/","orphanet_url":"https://www.orpha.net/en/disease/detail/98980","names":{"fr":{"name":"Syndrome de Cogan-Reese","definition":"Le syndrome de Cogan-Reese est une forme de syndrome irido-cornéo-endothélial (ICE) caractérisée par une atrophie irienne variable, des nodules iriens pigmentés et pédiculés et des anomalies de la cornée. Le glaucome secondaire est une complication fréquente de la maladie."},"de":{"name":"Cogan-Reese-Syndrom","definition":"Das Cogan-Reese-Syndrom ist eine klinische Variante des Irido-kornealen (ICE) Syndroms (s. dort). Kennzeichen sind unterschiedlich schwere Irisatrophie, pigmentierte gestielte Irisknötchen und Anomalien der Hornhaut. Sekundäres Glaukom ist eine häufige Komplikation der Krankheit."},"es":{"name":"Síndrome de Cogan-Reese","definition":"Es una variante clínica del síndrome endotelial iridocorneal (ICE) que se caracteriza por una atrofia variable del iris, nódulos pigmentados y pedunculados en el iris, y anomalías corneales. El glaucoma secundario es también una complicación frecuente de esta enfermedad."},"it":{"name":"Sindrome di Cogan-Reese","definition":"La sindrome di Cogan-Reese è una variante clinica della sindrome endoteliale iridocorneale (ICE; si veda questo termine), caratterizzata da atrofia variabile dell'iride, noduli peduncolati e pigmentati a livello dell'iride e anomalie della cornea. Il glaucoma secondario è una complicazione comune della malattia."},"nl":{"name":"Syndroom van Cogan-Reese","definition":"Een klinische variant van iridocorneaal endotheliaal (ICE) syndroom, gekarakteriseerd door variabele irisatrofie, gepigmenteerde en gesteelde noduli van de iris, en afwijkingen van het hoornvlies. Secundair glaucoom is ook een gangbare complicatie van de ziekte."},"pt":{"name":"Síndrome Cogan-Reese"},"pl":{"name":"Zespół Cogana i Reese'a"},"cs":{"name":"Coganův-Reeseho syndrom","synonyms":["Cogan-Reeseho syndrom"]},"uk":{"name":"Синдром Когана-Різа","definition":"A clinical variant of iridocorneal endothelial (ICE) syndrome, characterized by variable iris atrophy, pigmented and pedunculated nodules on the iris and corneal abonormalities. Secondary glaucoma is also a common complication of the disease."},"zh":{"name":"Cogan-Reese综合征","definition":"该病是虹膜角膜内皮综合征(ICE)的一种临床亚型，特征是虹膜萎缩程度不一，虹膜色素结节，带蒂结节和角膜异常，继发性青光眼也是该病的常见并发症。"},"tr":{"name":"Cogan-Reese sendromu"}},"xrefs":[{"source":"ICD-10","code":"H21.2","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LA11.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1968906450"},{"source":"MONDO","code":"0020370","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1168173","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"6125","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10059200","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":64734,"name":"Iridocorneal endothelial syndrome","classifications":[147,156,189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}