{"orpha":98951,"name":"Inverse Marcus-Gunn phenomenon","type":"Clinical subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":[],"definition":"Inverse Marcus-Gunn phenomenon is a rare congenital synkinesis where jaw opening by the pterygoid muscle (during eating or yawning) causes eyelid drooping from inhibition of the oculomotor nerve to the levator palpebrae superioris. Familial occurrence has been reported.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-98951/","orphanet_url":"https://www.orpha.net/en/disease/detail/98951","names":{"fr":{"name":"Phénomène de Marcus-Gunn inversé","definition":"Syncinésie congénitale rare où l'ouverture de la mâchoire par le muscle ptérygoïdien (lorsque l'on mange ou l'on bâille) provoque une chute de la paupière due à l'inhibition du nerf oculomoteur du muscle releveur de la paupière supérieure. Des cas familiaux ont été rapportés."},"de":{"name":"Inverses Marcus-Gunn-Phänomen","definition":"Das Inverse Marcus-Gunn-Phänomen ist eine seltene kongenitale Synkinesie: Beim Öffnen des Mundes durch den Pterygoid-Muskel (während des Essens oder Gähnens) erfolgt eine Senkung der Lider, weil die Innervierung des Levator-palpebrae-Muskels durch den Nervus oculomotorius gehemmt ist. Über familiäres Auftreten wurde berichtet."},"es":{"name":"Fenómeno de Marcus-Gunn invertido","definition":"El fenómeno de Marcus-Gunn invertido es una sincinesia congénita poco frecuente en la que la apertura de la mandíbula mediante el músculo pterigoideo (al comer o bostezar) provoca el cierre de los párpados por inhibición del nervio oculomotor del músculo elevador del párpado superior. Se ha informado de ocurrencia familiar."},"it":{"name":"Fenomeno inverso di Marcus-Gunn","definition":"Il fenomeno inverso di Marcus-Gunn è una sincinesia congenita rara nella quale l'apertura della mascella da parte del muscolo pterigoide (mentre si mangia o si sbadiglia) provoca la chiusura delle palpebre a causa dell'inibizione del nervo oculomotorio da parte del muscolo superiore elevatore della palpebra. È stata osservata una ricorrenza familiare."},"nl":{"name":"Omgekeerd fenomeen van Marcus-Gunn","definition":"Een zeldzame congenitale synkinese, waarbij opening van mond door musculus pterygoideus (tijdens eten of geeuwen) leidt tot hangend ooglid door inhibitie van innervatie van musculus levator palpebrae superioris door nervus oculomotorius. Familiaal voorkomen van omgekeerd Marcus-Gunn-fenomeen werd reeds gerapporteerd."},"pt":{"name":"Fenómeno de Marcus-Gunn inverso"},"pl":{"name":"Odwrócony fenomen Marcusa i Gunna"},"cs":{"name":"Inverzní fenomén Marcuse Gunna"},"uk":{"name":"Зворотній симптом Маркуса-Гунна","definition":"Inverse Marcus-Gunn phenomenon is a rare congenital synkinesis where jaw opening by the pterygoid muscle (during eating or yawning) causes eyelid drooping from inhibition of the oculomotor nerve to the levator palpebrae superioris. Familial occurrence has been reported."},"zh":{"name":"逆颌动瞬目现象","definition":"反向Marcus-Gunn现象是一种罕见的先天性联带运动，在进食或打哈欠时，翼状肌的张开会导致眼睑下垂，抑制从动眼神经到上睑提肌。家族发病已有报道。"},"tr":{"name":"Ters Marcus-Gunn fenomeni"}},"xrefs":[{"source":"ICD-10","code":"Q07.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"9A03.00","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"348052110"},{"source":"MONDO","code":"0020362","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5548210","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":91412,"name":"Marcus-Gunn syndrome","classifications":[147,156,189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}