{"orpha":98843,"name":"Classic Hodgkin lymphoma, nodular sclerosis type","type":"Histopathological subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":[],"definition":null,"note":"This disease is described under Classic Hodgkin lymphoma","url":"https://raremap.alftech.space/d/ORPHA-98843/","orphanet_url":"https://www.orpha.net/en/disease/detail/98843","names":{"fr":{"name":"Lymphome de Hodgkin classique type sclérosant nodulaire"},"de":{"name":"Klassisches Hodgkin-Lymphom, nodulär-sklerosierendes"},"es":{"name":"Linfoma de Hodgkin clásico con esclerosis nodular"},"it":{"name":"Linfoma di Hodgkin classico, tipo nodulare sclerosante"},"nl":{"name":"Klassiek Hodgkin-lymfoom, type nodulaire sclerose"},"pt":{"name":"Linfoma de Hodgkin clássico, esclerose nodular"},"pl":{"name":"Klasyczny chłoniak Hodgkina, typ ze stwardnieniem guzkowym"},"cs":{"name":"Klasický Hodgkinův lymfom, typ nodulární sklerózy"},"uk":{"name":"Класична лімфома Ходжкіна, тип вузликового склерозу"},"zh":{"name":"经典霍奇金淋巴瘤结节硬化型"},"tr":{"name":"Klasik Hodgkin lenfoma, nodüler skleroz tipi"}},"xrefs":[{"source":"ICD-10","code":"C81.1","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"2B30.10","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1995941600"},{"source":"MONDO","code":"0020327","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"4665","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0152268","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10020244","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":391,"name":"Classic Hodgkin lymphoma","classifications":[194,202,233]}],"children":[],"genes":[{"symbol":"KLHDC8B","name":"kelch domain containing 8B","gene_type":"gene with protein product","association":"Candidate gene tested in","status":"Not yet assessed","source":"19706467[PMID]","hgnc":"28557","ensembl":"ENSG00000185909","omim":"613169","loci":["3p21.31"]}],"genes_via_subtypes":[],"inheritance":[],"onset":["Adult"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.28,"area":"Europe","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"}],"phenotypes":null}