{"orpha":98819,"name":"Familial temporal lobe epilepsy","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare, genetic epilepsy characterized by mostly benign simple or complex partial seizures with autonomic or psychic auras. Seizures occur infrequently, are of short duration and are usually well controlled with medication. Development and cognition are normal.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-98819/","orphanet_url":"https://www.orpha.net/en/disease/detail/98819","names":{"fr":{"name":"Epilepsie temporale familiale","definition":"Épilepsie rare de cause génétique caractérisée par des crises partielles simples ou complexes, le plus souvent bénignes, avec auras autonomiques ou psychiques. Les crises sont peu fréquentes, de courte durée et généralement bien contrôlées par des médicaments. Le développement et la cognition sont normaux."},"de":{"name":"Temporallappenepilepsie, familiäre"},"es":{"name":"Epilepsia familiar del lóbulo temporal","definition":"Es una epilepsia genética poco frecuente caracterizada por crisis parciales simples o complejas, en su mayoría benignas, con auras autonómicas o psíquicas. Las crisis ocurren con poca frecuencia, son de corta duración y, por lo general, se pueden controlar adecuadamente con medicación. El desarrollo y la cognición son normales."},"it":{"name":"Epilessia del lobo temporale familiare","definition":"È un'epilessia genetica rara caratterizzata da crisi epilettiche parziali semplici o complesse per lo più benigne accompagnate da aure autonomiche o psichiche. Le crisi sono rare, di breve durata e di solito rispondono bene alla terapia farmacologica. Lo sviluppo e l'intelligenza sono normali."},"nl":{"name":"Familiale temporaalkwabepilepsie","synonyms":["Familiale TLE","Familiale epilepsie van de temporale kwab"],"definition":"Een zeldzame, genetische epilepsie die gekarakteriseerd wordt door meestal goedaardige, eenvoudige of complexe partiële insulten met autonome of psychische aura's. Insulten komen sporadisch voor, zijn van korte duur en zijn meestal goed controleerbaar met medicatie. Ontwikkeling en cognitie zijn normaal."},"pt":{"name":"Epilepsia temporal, familiar"},"pl":{"name":"Rodzinna padaczka skroniowa"},"cs":{"name":"Familiární temporální epilepsie"},"uk":{"name":"Сімейна скронева епілепсія","definition":"A rare, genetic epilepsy characterized by mostly benign simple or complex partial seizures with autonomic or psychic auras. Seizures occur infrequently, are of short duration and are usually well controlled with medication. Development and cognition are normal."},"zh":{"name":"家族性颞叶癫痫","definition":"一种罕见的遗传性癫痫，以良性单纯性或复杂性部分癫痫发作为特征，伴有自主神经或精神前驱症状。癫痫发作少见，持续时间短，通常通过药物治疗可以得到很好的控制，发育和认知都正常。"},"tr":{"name":"Ailesel temporal lob epilepsisi"}},"xrefs":[{"source":"OMIM","code":"608096","qualifier":"E","icd_relation":null,"validated":true},{"source":"OMIM","code":"611631","qualifier":"BTNT","icd_relation":null,"validated":false},{"source":"ICD-10","code":"G40.2","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"8A61.4Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"737749845"},{"source":"MONDO","code":"0005115","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"5115","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"C536956","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1842564","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"5135","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":98259,"name":"Childhood-onset epilepsy syndrome","classifications":[156,181]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}