{"orpha":98375,"name":"Autoimmune hemolytic anemia","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["AHA","AIHA"],"definition":"A rare, autoimmune disorder in which various types of auto-antibodies are directed against red blood cells causing their survival to be shortened and resulting in hemolytic anemia.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-98375/","orphanet_url":"https://www.orpha.net/en/disease/detail/98375","names":{"fr":{"name":"Anémie hémolytique auto-immune","synonyms":["AHA","AHAI","AIHA"],"definition":"L'anémie hémolytique auto-immune (AHAI) est une pathologie auto-immune au cours de laquelle divers types d'auto-anticorps anti-érythrocytaires raccourcissent la durée de vie des hématies et provoquent une anémie hémolytique."},"de":{"name":"Anämie, autoimmun-hämolytische","definition":"Die Autoimmun-hämolytische Anämie (AIHA) ist eine Autoimmunerkrankung mit verschiedenen gegen die Erythrozyten gerichteten Autoantikörpern. Dies führt zu verkürzter Lebensdauer der Erythrozyten und zu hämolytischer Anämie."},"es":{"name":"Anemia hemolítica autoinmune","synonyms":["AHA","AHAI"],"definition":"Es un trastorno autoinmune en el que varios tipos de autoanticuerpos están dirigidos directamente contra los glóbulos rojos lo que acorta su supervivencia provocando una anemia hemolítica."},"it":{"name":"Anemia emolitica autoimmune","synonyms":["AHA","AIHA"]},"nl":{"name":"Auto-immune hemolytische anemie","synonyms":["AHA","AIHA"],"definition":"Een zeldzame, auto-immune aandoening waarbij verschillende types van auto-antilichamen gericht zijn tegen rode bloedcellen, wat hun overleving verkort en resulteert in hemolytische anemie."},"pt":{"name":"Anemia hemolítica autoimune","definition":"A anemia hemolítica autoimune (AHAI) é uma patologia autoimune em que vários tipos de autoanticorpos são dirigidos contra os glóbulos vermelhos do sangue fazendo com que a sua sobrevivência seja encurtada e resultando em anemia hemolítica."},"pl":{"name":"Autoimmunologiczna niedokrwistość hemolityczna","synonyms":["AHA","AIHA"]},"cs":{"name":"Autoimunitní hemolytická anémie","synonyms":["AHA","AIHA"]},"uk":{"name":"Аутоімунна гемолітична анемія","synonyms":["АНА","AIHA"],"definition":"A rare, autoimmune disorder in which various types of auto-antibodies are directed against red blood cells causing their survival to be shortened and resulting in hemolytic anemia."},"zh":{"name":"自身免疫性溶血性贫血","synonyms":["自免溶贫"],"definition":"一种罕见的自身免疫性疾病，各种类型的自身抗体直接作用于红细胞，使红细胞存活时间缩短，导致溶血性贫血。"},"tr":{"name":"Otoimmün hemolitik anemi","synonyms":["AHA","AIHA"]}},"xrefs":[{"source":"ICD-11","code":"3A20","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1834341306"},{"source":"MONDO","code":"0020108","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D000744","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0002880","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"5870","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10002046","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97992,"name":"Rare hematologic disease"},"parents":[{"orpha":182047,"name":"Rare acquired hemolytic anemia","classifications":[194]}],"children":[{"orpha":228312,"name":"Autoimmune hemolytic anemia, cold type","type":"Clinical group"},{"orpha":90033,"name":"Autoimmune hemolytic anemia, warm type","type":"Disease"},{"orpha":90037,"name":"Drug-induced autoimmune hemolytic anemia","type":"Disease"},{"orpha":1959,"name":"Evans syndrome","type":"Disease"},{"orpha":90036,"name":"Mixed-type autoimmune hemolytic anemia","type":"Disease"},{"orpha":438159,"name":"STAT3-related early-onset multisystem autoimmune disease","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":["Multigenic/multifactorial"],"onset":["All ages"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":2.02,"area":"Europe","status":"Validated","source":"[EXPERT]_ORPHANET"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":2.02,"area":"United States","status":"Validated","source":"[EXPERT]_ORPHANET"},{"type":"Point prevalence","qualification":"Value and class","class":"1-5 / 10 000","value":11.0,"area":"Denmark","status":"Validated","source":"20066507[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"1-9 / 100 000","value":0.0,"area":"Europe","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}