{"orpha":97361,"name":"Renal hypoplasia, unilateral","type":"Clinical subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":[],"definition":"A form of renal hypoplasia characterized by unilateral abnormally small kidneys with reduced number of nephrons. Patients are usually asymptomatic however some patients may present with hypertension and urinary tract infections. Risk of renal failure in childhood is minimal.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-97361/","orphanet_url":"https://www.orpha.net/en/disease/detail/97361","names":{"fr":{"name":"Hypoplasie rénale unilatérale","definition":"Forme d'hypoplasie rénale caractérisée par une taille anormalement petite de l'un des reins et un nombre réduit de néphrons. Les patients sont généralement asymptomatiques, mais certains peuvent présenter une hypertension artérielle et des infections des voies urinaires. Le risque d'insuffisance rénale pendant l'enfance est minime."},"de":{"name":"Nierenhypoplasie, unilaterale","definition":"Eine Form der Nierenhypoplasie, die durch einseitig abnorm kleine Nieren mit verminderter Anzahl von Nephronen gekennzeichnet ist. Die Patienten sind in der Regel asymptomatisch, jedoch können bei einigen Patienten Bluthochdruck und Harnwegsinfektionen auftreten. Das Risiko eines Nierenversagens im Kindesalter ist minimal."},"es":{"name":"Hipoplasia renal unilateral","definition":"Es una forma de hipoplasia renal caracterizada por riñones unilaterales anormalmente pequeños con un número reducido de nefronas. Los pacientes suelen permanecer asintomáticos, aunque algunos pueden presentar hipertensión e infecciones del tracto urinario. El riesgo de insuficiencia renal en la infancia es mínimo."},"it":{"name":"Ipoplasia renale unilaterale","definition":"L'ipoplasia renale unilaterale è una forma di ipoplasia renale (si veda questo termine), un'anomalia dello sviluppo renale in cui un rene ha dimensioni ridotte e presenta un numero deficitario di nefroni."},"nl":{"name":"Unilaterale renale hypoplasie","definition":"Een vorm van hypoplasie van nier, gekenmerkt door unilateraal abnormaal kleine nier met een verminderd aantal nefronen. Patiënten zijn meestal asymptomatisch, maar sommige patiënten vertonen mogelijk hypertensie en urineweginfecties. Het risico op nierfalen in de kindertijd is minimaal."},"pt":{"name":"Hipoplasia renal, unilateral"},"pl":{"name":"Hipoplazja nerki, jednostronna"},"cs":{"name":"Renální hypoplázie, jednostranná"},"uk":{"name":"Гіпоплазія нирок, одностороння","definition":"A form of renal hypoplasia characterized by unilateral small kidneys with a deficit in the number of nephrons present. The condition is typically asymptomatic with minimal risk of renal failure in childhood"},"zh":{"name":"单侧肾发育不全","definition":"该病是肾发育不全的一种形式，其特征是单侧肾缩小伴肾单位数量不足。这种情况通常是无症状的，在儿童时期发生肾功能衰竭的风险很小。"},"tr":{"name":"Renal hipoplazi, unilateral"}},"xrefs":[{"source":"ICD-10","code":"Q60.3","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"LB30.0Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1509712053"},{"source":"MONDO","code":"0019979","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0431691","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":93101,"name":"Renal hypoplasia","classifications":[147,156,188,233]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"[EXPERT]"}],"phenotypes":null}