{"orpha":97349,"name":"Postencephalitic parkinsonism","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":null,"note":null,"url":"https://raremap.alftech.space/d/ORPHA-97349/","orphanet_url":"https://www.orpha.net/en/disease/detail/97349","names":{"fr":{"name":"Parkinsonisme postencéphalitique"},"de":{"name":"Postenzephalitisches Parkinson-Syndrom"},"es":{"name":"Parkinsonismo postencefálico"},"it":{"name":"Parkinsonismo post-encefalitico"},"nl":{"name":"Postencefalitisch parkinsonisme"},"pt":{"name":"Parkinsonismo pós-encefalite"},"pl":{"name":"Parkinsonizm pozapalny"},"cs":{"name":"Postencefalitický parkinsonismus"},"uk":{"name":"Постенцефалічний паркінсонізм"},"zh":{"name":"脑炎后帕金森症"},"tr":{"name":"Postensefalitik parkinsonizm"}},"xrefs":[{"source":"ICD-10","code":"G21.3","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"8A00.22","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1939015306"},{"source":"MONDO","code":"0001945","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D010301","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0030568","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"19370","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":98542,"name":"Infectious disease with dementia","classifications":[181]},{"orpha":306666,"name":"Rare parkinsonian syndrome due to neurodegenerative disease","classifications":[181]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Adult","Elderly"],"prevalence":[],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2018-03-23","source":"7299406[PMID]","terms":[{"hpo":"HP:0002322","label":"Resting tremor","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0007256","label":"Abnormal pyramidal sign","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0003487","label":"Babinski sign","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002067","label":"Bradykinesia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002396","label":"Cogwheel rigidity","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002329","label":"Drowsiness","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001945","label":"Fever","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0003324","label":"Generalized muscle weakness","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0004305","label":"Involuntary movements","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0010553","label":"Oculogyric crisis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002465","label":"Poor speech","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0025456","label":"Abnormal CSF protein level","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002795","label":"Abnormal respiratory system physiology","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000496","label":"Abnormality of eye movement","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0011446","label":"Abnormality of higher mental function","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0045007","label":"Abnormality of the substantia nigra","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000718","label":"Aggressive behavior","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002304","label":"Akinesia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002381","label":"Aphasia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0008765","label":"Auditory hallucinations","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001488","label":"Bilateral ptosis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0200149","label":"CSF lymphocytic pleiocytosis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100595","label":"Camptocormia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012735","label":"Cough","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000716","label":"Depression","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002374","label":"Diminished movement","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001260","label":"Dysarthria","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002015","label":"Dysphagia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0005329","label":"Fixed facial expression","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0040082","label":"Happy demeanor","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002315","label":"Headache","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0006801","label":"Hyperactive deep tendon reflexes","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002808","label":"Kyphosis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000194","label":"Open mouth","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003401","label":"Paresthesia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002063","label":"Rigidity","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001250","label":"Seizure","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000514","label":"Slow saccadic eye movements","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030188","label":"Tremor by anatomical site","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0025331","label":"Upgaze palsy","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002013","label":"Vomiting","frequency":"Occasional (29-5%)","criteria":null}]}}