{"orpha":97336,"name":"Panner disease","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Aseptic necrosis of the capital humerus","Osteochondrosis of the capital humerus"],"definition":"A rare osteochondrosis of the capitellum of the humerus, characterized by involvement of the dominant upper limb and onset before the age of 10 years. It results from lateral compression injuries of the elbow typically occurring in children practising sports such as baseball and throw. It should be distinguished from osteochondritis dissecans of the capitellum, occurring later, in adolescents.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-97336/","orphanet_url":"https://www.orpha.net/en/disease/detail/97336","names":{"fr":{"name":"Maladie de Panner","synonyms":["Nécrose aseptique des condyles huméraux","Ostéochondrite des condyles huméraux"],"definition":"Ostéochondrite des condyles huméraux, caractérisée par l'atteinte du bras dominant et un début avant l'âge de 10 ans. Elle est provoquée par des blessures par compression latérale du coude, se produisant classiquement chez des enfants pratiquant des sports comme le baseball et le lancer. Il faut distinguer la maladie de Panner de l'ostéochondrite disséquante des condyles huméraux , se produisant plus tard, à l'adolescence. Le traitement des symptômes consiste à réduire l'activité du coude atteint pendant une longue durée. Le pronostic est bon."},"de":{"name":"Panner-Krankheit","synonyms":["Aseptische Nekrose des Capitulum humeri","Osteochondrose des Capitulum humeri"],"definition":"Die Panner-Krankheit ist eine Osteochondrose des <i>Capitulum humeri</i> (Teil de distalen Humerusgelenks). Die Krankheit tritt vor dem 10. Lebensjahr am dominanten Arm auf."},"es":{"name":"Enfermedad de Panner","synonyms":["Necrosis aséptica de la cabeza del húmero","Necrosis aséptica del capítulo del húmero","Osteocondrosis de la cabeza del húmero","Osteocondrosis del capítulo del húmero"],"definition":"Es una osteocondrosis poco frecuente del capitellum del húmero caracterizada por la afectación de la extremidad superior dominante de inicio antes de los 10 años de edad. Es el resultado de lesiones por compresión lateral del codo que ocurren típicamente en niños que practican deportes como el béisbol y el lanzamiento. Debe distinguirse de la osteocondritis disecante del capitellum, que ocurre más tarde, en la adolescencia."},"it":{"name":"Malattia di Panner","synonyms":["Necrosi asettica dei condili omerali","Osteocondrosi dei condili omerali"]},"nl":{"name":"Ziekte van Panner","synonyms":["Aseptische necrose van de humeruskop","Osteochondrose van de humeruskop"],"definition":"Ziekte van Panner is een osteochondrose van capitulum humeri (humeruskopje), gekenmerkt door betrokkenheid van dominant bovenste ledemaat en aanvang voor de leeftijd van 10 jaar. Het is het gevolg van laterale letsels door compressie van elleboog die doorgaans optreden bij kinderen die sporten zoals baseball en gooien uitoefenen. Het dient onderscheiden te worden van osteochondritis dissecans van capitulum humeri, dat later optreedt bij adolescenten. Ziektebeheer is symptomatisch en bestaat uit verminderen van de activiteiten van de aangetaste elleboog gedurende een langere periode. De prognose is gunstig."},"pt":{"name":"Doença de Panner"},"pl":{"name":"Choroba Pannera","synonyms":["Jałowa martwica głowy kości ramiennej","Osteochondroza głowy kości ramiennej"]},"cs":{"name":"Pannerova nemoc","synonyms":["Aseptická nekróza hlavice humeru","Osteochondróza hlavice humeru"]},"uk":{"name":"Хвороба Паннера","synonyms":["Асептичний некроз великогомілкової кістки","Остеохондроз головки плечової кістки"],"definition":"A rare osteochondrosis of the capitellum of the humerus, characterized by involvement of the dominant upper limb and onset before the age of 10 years. It results from lateral compression injuries of the elbow typically occurring in children practising sports such as baseball and throw. It should be distinguished from osteochondritis dissecans of the capitellum, occurring later, in adolescents."},"zh":{"name":"Panner病","synonyms":["肱骨小头无菌性坏死"],"definition":"Panner病是一种肱骨小头骨软骨病，其特点是累及主要上肢，发病年龄在10岁以前。它是由肘部的侧挤压伤引起的，通常发生在儿童练习棒球和投掷等运动中。它应该与后来发生于青少年的小头剥离性骨软骨炎（见该词条）相区别。有症状的需要进行管理，例如在一段时间内减少受影响肘关节的活动。预后良好。"},"tr":{"name":"Panner hastalığı","synonyms":["Baş humerusun osteokondrozu","Baş humerusun aseptik nekrozu"]}},"xrefs":[{"source":"ICD-10","code":"M92.0","qualifier":"NTBT","icd_relation":"inclusion","validated":true},{"source":"ICD-11","code":"FB82.1","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"983679911"},{"source":"MONDO","code":"0019969","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4759831","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93419,"name":"Rare bone disease"},"parents":[{"orpha":399319,"name":"Osteochondrosis","classifications":[196,199]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Childhood"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2019-06-14","source":"30483677[PMID]_25663360[PMID]","terms":[{"hpo":"HP:0009810","label":"Abnormality of upper limb joint","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0040188","label":"Osteochondrosis","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0031095","label":"Abnormal humerus morphology","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0030835","label":"Elbow pain","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001386","label":"Joint swelling","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001377","label":"Limited elbow extension","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002996","label":"Limited elbow movement","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001871","label":"Abnormality of blood and blood-forming tissues","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003945","label":"Irregular articular surfaces of the elbow joints","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030865","label":"Large elbow","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0025259","label":"Stiff elbow","frequency":"Occasional (29-5%)","criteria":null}]}}